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前列腺癌治疗后的性康复——第1部分:第四届国际性医学咨询会议(ICSM 2015)的建议

Sexual Rehabilitation After Treatment for Prostate Cancer-Part 1: Recommendations From the Fourth International Consultation for Sexual Medicine (ICSM 2015).

作者信息

Salonia Andrea, Adaikan Ganesh, Buvat Jacques, Carrier Serge, El-Meliegy Amr, Hatzimouratidis Kostas, McCullough Andrew, Morgentaler Abraham, Torres Luiz Otavio, Khera Mohit

机构信息

Università Vita-Salute San Raffaele, Milan, Italy.

Section of Sexual Medicine, Obstetrics and Gynaecology, National University Hospital, National University of Singapore, Singapore.

出版信息

J Sex Med. 2017 Mar;14(3):285-296. doi: 10.1016/j.jsxm.2016.11.325.

Abstract

INTRODUCTION

Sexual dysfunction is common in patients after radical prostatectomy (RP) for prostate cancer.

AIM

To provide the International Consultation for Sexual Medicine (ICSM) 2015 recommendations concerning prevention and management strategies for post-RP erectile function impairment in terms of preoperative patient characteristics and intraoperative factors that could influence erectile function recovery.

METHODS

A literature search was performed using Google and PubMed databases for English-language original and review articles published up to August 2016.

MAIN OUTCOME MEASURES

Levels of evidence (LEs) and grades of recommendations (GRs) based on a thorough analysis of the literature and committee consensus.

RESULTS

Nine recommendations are provided by the ICSM 2015 committee on sexual rehabilitation after RP. Recommendation 1 states that clinicians should discuss the occurrence of postsurgical erectile dysfunction (temporary or permanent) with every candidate for RP (expert opinion, clinical principle). Recommendation 2 states that validated instruments for assessing erectile function recovery such as the International Index of Erectile Function and Expanded Prostate Cancer Index Composite questionnaires are available to monitor EF recovery after RP (LE = 1, GR = A). Recommendation 3 states there is insufficient evidence that a specific surgical technique (open vs laparoscopic vs robot-assisted radical prostatectomy) promotes better results in postoperative EF recovery (LE = 2, GR = C). Recommendation 4 states that recognized predictors of EF recovery include but are not limited to younger age, preoperative EF, and bilateral nerve-sparing surgery (LE = 2, GR = B). Recommendation 5 states that patients should be informed about key elements of the pathophysiology of postoperative erectile dysfunction, such as nerve injury and cavernous venous leak (expert opinion, clinical principle).

CONCLUSIONS

This article discusses Recommendations 1 to 5 of the ICSM 2015 committee on sexual rehabilitation after RP. Salonia A, Adaikan G, Buvat J, et al. Sexual Rehabilitation After Treatment for Prostate Cancer-Part 1: Recommendations From the Fourth International Consultation for Sexual Medicine (ICSM 2015). J Sex Med 2017;14:285-296.

摘要

引言

性功能障碍在前列腺癌根治术(RP)后的患者中很常见。

目的

根据术前患者特征和可能影响勃起功能恢复的术中因素,提供国际性医学咨询会议(ICSM)2015年关于RP后勃起功能障碍预防和管理策略的建议。

方法

使用谷歌和PubMed数据库检索截至2016年8月发表的英文原创和综述文章。

主要观察指标

基于对文献的全面分析和委员会共识的证据水平(LEs)和推荐等级(GRs)。

结果

ICSM 2015委员会提供了九条关于RP后性康复的建议。建议1指出,临床医生应与每位RP候选患者讨论术后勃起功能障碍(暂时性或永久性)的发生情况(专家意见,临床原则)。建议2指出,有经过验证的评估勃起功能恢复的工具,如国际勃起功能指数和扩展前列腺癌指数综合问卷,可用于监测RP后勃起功能的恢复情况(LE = 1,GR = A)。建议3指出,没有足够证据表明特定的手术技术(开放手术、腹腔镜手术或机器人辅助根治性前列腺切除术)能在术后勃起功能恢复方面取得更好的效果(LE = 2,GR = C)。建议4指出,公认的勃起功能恢复预测因素包括但不限于年轻、术前勃起功能和双侧神经保留手术(LE = 2,GR = B)。建议5指出,应告知患者术后勃起功能障碍病理生理学的关键要素,如神经损伤和海绵体静脉漏(专家意见,临床原则)。

结论

本文讨论了ICSM 2015委员会关于RP后性康复的建议1至5。萨洛尼亚A、阿达伊坎G、比瓦特J等。前列腺癌治疗后的性康复——第1部分:第四届国际性医学咨询会议(ICSM 2015)的建议。《性医学杂志》2017年;14:285 - 296。

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