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单中心心房颤动迷宫术后起搏器植入经验。

A single center's experience with pacemaker implantation after the Cox maze procedure for atrial fibrillation.

机构信息

Department of Cardiovascular and Thoracic Surgery, West Virginia University, Morgantown, WVa.

Heart and Vascular Institute, West Virginia University Medicine, Morgantown, WVa.

出版信息

J Thorac Cardiovasc Surg. 2017 Jul;154(1):139-146.e1. doi: 10.1016/j.jtcvs.2016.12.047. Epub 2017 Feb 9.

Abstract

OBJECTIVE

The Cox maze procedure (CM) is safe and effective for all atrial fibrillation (AF) types. A recent randomized trial found alarming rates of pacemaker implantation (PMI) during hospitalization after CM. The purpose of this study was to assess the rate of PMI and its impact on outcomes after CM.

METHODS

Incidence of PMI was captured for all CM patients (2005-2015; N = 739). Data were collected prospectively. Multivariable logistic regression was conducted to determine risk factors for PMI. Propensity score matching was conducted between concomitant CM patients and patients without surgical ablation since 2011.

RESULTS

Fifty-two patients (7.0%) had in-hospital PMI after CM. Most common primary indication for PMI was sick sinus syndrome (67%), followed by complete heart block (23%) and sinus bradycardia (10%). The only risk factor for in-hospital PMI was type of procedure (P = .020). Patients with multiple valve procedures were at greatest risk (P = .004-.035). STS-defined perioperative outcomes were similar for patients with and without in-hospital PMI. Sinus rhythm off antiarrhythmic drugs were similar by PMI. After propensity score matching (n = 180 per group), in-hospital PMI was similar in CM patients and those without surgical ablation (5% vs 4%, P = .609).

CONCLUSIONS

This study demonstrated lower incidence of PMI after CM procedures than recently reported. When indicated, PMI was not associated with increased short- or long-term morbidity or inferior freedom from atrial arrhythmia. Efforts to increase surgeon training with the CM procedure and postoperative management awareness are warranted to improve rhythm outcome and minimize adverse events and PMI.

摘要

目的

Cox 迷宫手术(CM)对所有类型的心房颤动(AF)均安全有效。最近的一项随机试验发现,CM 术后住院期间起搏器植入(PMI)的发生率惊人。本研究旨在评估 CM 后 PMI 的发生率及其对结果的影响。

方法

记录所有 CM 患者(2005-2015 年;N=739)的 PMI 发生率。数据前瞻性收集。多变量逻辑回归确定 PMI 的危险因素。由于 2011 年以来进行了 CM 联合手术消融的患者与未行手术消融的患者之间进行了倾向评分匹配。

结果

52 例患者(7.0%)在 CM 后住院期间发生 PMI。PMI 的主要原发性指征是病窦综合征(67%),其次是完全性心脏阻滞(23%)和窦性心动过缓(10%)。住院期间 PMI 的唯一危险因素是手术类型(P=0.020)。多瓣膜手术患者的风险最大(P=0.004-0.035)。STS 定义的围手术期结局对于有无住院 PMI 的患者相似。PMI 后抗心律失常药物停用时的窦性节律相似。进行倾向评分匹配(每组 n=180)后,CM 患者和未行手术消融的患者住院期间 PMI 相似(5%比 4%,P=0.609)。

结论

本研究表明 CM 术后 PMI 的发生率低于最近的报道。当需要时,PMI 与短期和长期发病率增加或房性心律失常的无复发率降低无关。需要努力提高 CM 手术和术后管理意识的外科医生培训,以改善节律结果并尽量减少不良事件和 PMI。

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