津巴布韦哈拉雷帕里仁亚瓦教学医院接受超声心动图检查的心血管疾病患者中的围产期心肌病。
Peripartum cardiomyopathy among cardiovascular patients referred for echocardiography at Parirenyatwa Teaching Hospital, Harare, Zimbabwe.
作者信息
Gambahaya Ellise Tapiwa, Hakim James, Kao David, Munyandu Noleen, Matenga Jonathan
机构信息
College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe. Email:
College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe.
出版信息
Cardiovasc J Afr. 2017 Jan/Feb;28(1):8-13. doi: 10.5830/CVJA-2016-043.
OBJECTIVES
The main aim was to evaluate the outcome of patients with peripartum cardiomyopathy (PPCM) within six months of diagnosis. The secondary aim was to describe demographic and clinical characteristics of patients with PPCM in Harare, Zimbabwe.
METHODS
This was a prospective cohort study in which patients recruited into a detailed PPCM registry were followed up for six months. Echocardiograms were performed at enrolment, and three and six months after diagnosis, to determine left ventricular function.
RESULTS
From 1 August 2012 to 31 July 2013, 43 patients with a new diagnosis of PPCM were recruited at Parirenyatwa Hospital in Harare. At six months, mean ejection fraction improved from 29.7 ± 9.8 to 44.9 ± 14.9%, p < 0.001 and New York Heart Association (NYHA) functional class improved significantly (p < 0.0001). Five (11.6%) patients died.
CONCLUSIONS
Left ventricular function improved in a substantial number of patients (42.9%) in this Zimbabwean cohort compared to other African cohorts. However the mortality rate remained high.
目的
主要目的是评估围产期心肌病（PPCM）患者在诊断后六个月内的预后。次要目的是描述津巴布韦哈拉雷PPCM患者的人口统计学和临床特征。
方法
这是一项前瞻性队列研究，将纳入详细PPCM登记册的患者随访六个月。在入组时、诊断后三个月和六个月进行超声心动图检查，以确定左心室功能。
结果
2012年8月1日至2013年7月31日，哈拉雷的帕里伦亚图瓦医院招募了43例新诊断为PPCM的患者。六个月时，平均射血分数从29.7±9.8提高到44.9±14.9%，p<0.001，纽约心脏协会（NYHA）功能分级显著改善（p<0.0001）。5例（11.6%）患者死亡。
结论
与其他非洲队列相比，该津巴布韦队列中相当数量（42.9%）的患者左心室功能有所改善。然而，死亡率仍然很高。
Zotero 插件