Jensen Christian F S, Fode Mikkel, Østergren Peter, Sønksen Jens
Ugeskr Laeger. 2017 Feb 27;179(9).
Hypogonadism and prostate cancer (PCa) often coincide with increasing age. Recent reviews have found no evidence to suggest an increased risk of developing PCa with testosterone replacement therapy (TRT). The same lack of PCa risk is found in studies looking at men receiving TRT after radical prostatectomy for PCa. Reports on TRT in men on active surveillance are very few. In summary, current evidence does not support an association between TRT and an increased risk of PCa. Nevertheless, sufficiently powered trials with longer follow-up are warranted before making final conclusions.
性腺功能减退和前列腺癌（PCa）常随年龄增长而同时出现。最近的综述未发现证据表明睾酮替代疗法（TRT）会增加患PCa的风险。在对因PCa接受根治性前列腺切除术后接受TRT的男性进行的研究中，也发现不存在PCa风险增加的情况。关于接受主动监测的男性使用TRT的报告非常少。总之，目前的证据不支持TRT与PCa风险增加之间存在关联。然而，在得出最终结论之前，有必要进行足够大规模且随访时间更长的试验。
