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别怕“恐惧条件作用”:关于人类恐惧习得、消退和恐惧重现研究设计与分析的方法学考量

Don't fear 'fear conditioning': Methodological considerations for the design and analysis of studies on human fear acquisition, extinction, and return of fear.

作者信息

Lonsdorf Tina B, Menz Mareike M, Andreatta Marta, Fullana Miguel A, Golkar Armita, Haaker Jan, Heitland Ivo, Hermann Andrea, Kuhn Manuel, Kruse Onno, Meir Drexler Shira, Meulders Ann, Nees Frauke, Pittig Andre, Richter Jan, Römer Sonja, Shiban Youssef, Schmitz Anja, Straube Benjamin, Vervliet Bram, Wendt Julia, Baas Johanna M P, Merz Christian J

机构信息

University Medical Center Hamburg-Eppendorf, Department of Systems Neuroscience, Hamburg, Germany.

University Medical Center Hamburg-Eppendorf, Department of Systems Neuroscience, Hamburg, Germany.

出版信息

Neurosci Biobehav Rev. 2017 Jun;77:247-285. doi: 10.1016/j.neubiorev.2017.02.026. Epub 2017 Mar 3.

DOI:10.1016/j.neubiorev.2017.02.026
PMID:28263758
Abstract

The so-called 'replicability crisis' has sparked methodological discussions in many areas of science in general, and in psychology in particular. This has led to recent endeavours to promote the transparency, rigour, and ultimately, replicability of research. Originating from this zeitgeist, the challenge to discuss critical issues on terminology, design, methods, and analysis considerations in fear conditioning research is taken up by this work, which involved representatives from fourteen of the major human fear conditioning laboratories in Europe. This compendium is intended to provide a basis for the development of a common procedural and terminology framework for the field of human fear conditioning. Whenever possible, we give general recommendations. When this is not feasible, we provide evidence-based guidance for methodological decisions on study design, outcome measures, and analyses. Importantly, this work is also intended to raise awareness and initiate discussions on crucial questions with respect to data collection, processing, statistical analyses, the impact of subtle procedural changes, and data reporting specifically tailored to the research on fear conditioning.

摘要

所谓的“可重复性危机”在科学的许多领域引发了方法学讨论,尤其是在心理学领域。这导致了近期为提高研究的透明度、严谨性以及最终的可重复性所做的努力。源于这种时代精神,这项工作承接了在恐惧条件反射研究中讨论术语、设计、方法和分析考量等关键问题的挑战,该工作涉及欧洲十四家主要人类恐惧条件反射实验室的代表。本汇编旨在为人类恐惧条件反射领域制定通用的程序和术语框架提供基础。只要有可能,我们会给出一般性建议。当这不可行时,我们会为研究设计、结果测量和分析的方法学决策提供基于证据的指导。重要的是,这项工作还旨在提高人们对数据收集、处理、统计分析、细微程序变化的影响以及专门针对恐惧条件反射研究的数据报告等关键问题的认识,并引发相关讨论。

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