University of Texas Health Science Center at San Antonio, San Antonio, TX.
Staten Island University Hospital, Staten Island, NY.
J Am Coll Surg. 2017 May;224(5):926-932. doi: 10.1016/j.jamcollsurg.2017.02.012. Epub 2017 Mar 2.
We sought to determine whether aggressive resuscitation in trauma patients presenting without vital signs, or "dead on arrival," was futile. We also sought to determine whether organ donation was an unexpected benefit of aggressive resuscitation.
We conducted a review of adults presenting to our Level I trauma center with no signs of life (pulse = 0 beats/min; systolic blood pressure = 0 mmHg; and no evidence of neurologic activity, Glasgow Coma Scale score = 3). Primary end point was survival to hospital discharge or major organ donation (ie heart, lung, kidney, liver, or pancreas were harvested). We compared our survival rates with those of the National Trauma Data Bank in 2012. Patient demographics, emergency department vital signs, and outcomes were analyzed.
Three hundred and forty patients presented with no signs of life to our emergency department after injury (median Injury Severity Score = 40). There were 7 survivors to discharge, but only 5 (1.5%) were functionally independent (4 were victims of penetrating trauma). Of the 333 nonsurvivors, 12 patients (3.6%) donated major organs (16 kidneys, 2 hearts, 4 livers, and 2 lungs). An analysis of the National Trauma Data Bank yielded a comparable survival rate for those presenting dead on arrival, with an overall survival rate of 1.8% (100 of 5,384); 2.3% for blunt trauma and 1.4% for penetrating trauma.
Trauma patients presenting dead on arrival rarely (1.5%) achieve functional independence. However, organ donation appears to be an under-recognized outcomes benefit (3.6%) of the resuscitation of injury victims arriving without vital signs.
我们旨在确定在没有生命迹象(即“到达时已死亡”)的创伤患者中进行积极复苏是否徒劳无益。我们还试图确定器官捐献是否是积极复苏的意外获益。
我们对我院一级创伤中心收治的无生命迹象的成年人(脉搏= 0 次/分;收缩压= 0 mmHg;且无神经活动迹象,格拉斯哥昏迷评分= 3)进行了回顾性研究。主要终点是存活至出院或主要器官捐献(即心脏、肺、肾、肝或胰腺被采集)。我们将我们的存活率与 2012 年国家创伤数据库的数据进行了比较。分析了患者的人口统计学特征、急诊科生命体征和结局。
340 名患者因受伤后到达急诊室时无生命迹象(中位数损伤严重程度评分= 40)。有 7 名患者出院时存活,但只有 5 名(1.5%)具有独立功能(4 名是穿透性创伤的受害者)。在 333 名非幸存者中,有 12 名患者(3.6%)捐献了主要器官(16 个肾脏、2 个心脏、4 个肝脏和 2 个肺)。对国家创伤数据库的分析得出了类似的到达时已死亡患者的存活率,总体存活率为 1.8%(5384 例中的 100 例);钝性创伤为 2.3%,穿透性创伤为 1.4%。
到达时已死亡的创伤患者很少(1.5%)能达到独立功能。然而,器官捐献似乎是复苏无生命迹象的创伤受害者的一个被低估的结局获益(3.6%)。