Koh Young Kwon, Lee Jae Hee, Park Yeong Bong
Department of Pediatrics,Chosun University School of Medicine,Gwangju,Republic of Korea.
Cardiol Young. 2017 Jul;27(5):1004-1007. doi: 10.1017/S1047951116002742. Epub 2017 Mar 7.
Disseminated intravascular coagulation is a rare complication of Kawasaki disease and appears in <0.1% of Kawasaki disease patients. We report a case of refractory Kawasaki disease complicated with disseminated intravascular coagulation and giant coronary aneurysm. A 5-month-old boy presented with Kawasaki disease with coagulopathy. Although the coagulopathy improved after fresh-frozen plasma and antithrombin-III administration, the fever persisted despite two rounds of intravenous immunoglobulin, along with intravenous methylprednisolone pulse therapy and infliximab administration. Despite all efforts to treatment, the patient had giant coronary aneurysms and died suddenly.
弥散性血管内凝血是川崎病的一种罕见并发症，在不到0.1%的川崎病患者中出现。我们报告一例难治性川崎病并发弥散性血管内凝血和巨大冠状动脉瘤的病例。一名5个月大的男孩因川崎病出现凝血病。尽管输注新鲜冷冻血浆和抗凝血酶III后凝血病有所改善，但尽管进行了两轮静脉注射免疫球蛋白、静脉注射甲泼尼龙冲击疗法和英夫利昔单抗治疗，发热仍持续。尽管全力治疗，该患者仍出现巨大冠状动脉瘤并突然死亡。
