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妊娠期高安动脉炎:来自印度一家三级医疗医院的罕见病例报告。

Takayasu's Arteritis in Pregnancy: A Rare Case Report from a Tertiary Care Infirmary in India.

作者信息

Marwah Sheeba, Rajput Monika, Mohindra Ritin, Gaikwad Harsha S, Sharma Manjula, Topden Sonam R

机构信息

Department of Obstetrics and Gynecology, VMMC and Safdarjung Hospital, New Delhi 110029, India.

Department of Internal Medicine, VMMC and Safdarjung Hospital, New Delhi 110029, India.

出版信息

Case Rep Obstet Gynecol. 2017;2017:2403451. doi: 10.1155/2017/2403451. Epub 2017 Feb 7.

Abstract

. Takayasu's arteritis (TA) is a rare, chronic, inflammatory, progressive, idiopathic arteriopathy, afflicting young women of reproductive age group, causing narrowing, occlusion, and aneurysms of systemic and pulmonary arteries, especially the aorta and its branches. During pregnancy, such patients warrant special attention. An interdisciplinary collaboration of obstetricians, cardiologists, and neurologists is necessary to improve maternal and fetal prognosis. Here a case is reported where a patient with diagnosis of TA, complicated by neurological sequelae, successfully fought the vagaries of the condition twice to deliver uneventfully. . 25-year-old G2P1L1 presented at 34 weeks of gestation, with chronic hypertension, with TA, with epilepsy, and with late-onset severe IUGR. Following a multidisciplinary approach, she delivered an alive born low birth weight baby (following induction). Her postpartum course remained uneventful. . Pregnancy with TA poses a stringent challenge to an obstetrician. Despite advancements in cardiovascular management and advent of new-fangled drugs, the optimal management for pregnant patients with this disease still remains elusive.

摘要

高安动脉炎(TA)是一种罕见的慢性炎症性进行性特发性动脉病,困扰育龄期年轻女性,导致全身和肺动脉,尤其是主动脉及其分支狭窄、闭塞和动脉瘤形成。在孕期,这类患者需要特别关注。产科医生、心脏病专家和神经科医生的多学科协作对于改善母婴预后至关重要。本文报告一例诊断为TA并伴有神经后遗症的患者,两次成功应对病情变化,顺利分娩。一名25岁、孕2产1、有1次活产史的孕妇在妊娠34周时就诊,患有慢性高血压、TA、癫痫和晚发型严重胎儿生长受限。经过多学科方法治疗,她分娩出一名活产低体重儿(引产之后)。她的产后过程顺利。TA患者妊娠对产科医生构成严峻挑战。尽管心血管管理取得进展且新型药物问世,但患有这种疾病的孕妇的最佳管理方法仍难以确定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe43/5318617/bd8cdb73e3e2/CRIOG2017-2403451.001.jpg

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