Nemni R, Bottacchi E, Fazio R, Mamoli A, Corbo M, Camerlingo M, Galardi G, Erenbourg L, Canal N
Department of Neurology, University of Milan, Italy.
J Neurol Neurosurg Psychiatry. 1987 Nov;50(11):1454-60. doi: 10.1136/jnnp.50.11.1454.
Clinical, neurophysiological and morphological studies of four patients with polyneuropathy and secondary hypothyroidism are reported. Neurophysiological studies revealed signs of muscle denervation and reduction of conduction velocity in all the patients. Sural nerve biopsies showed axonal degeneration in all cases but one. All the patients were treated with replacement therapy and clinical symptomatology and neurophysiological parameters improved in all patients.
报告了4例患有多发性神经病和继发性甲状腺功能减退患者的临床、神经生理学和形态学研究。神经生理学研究显示,所有患者均有肌肉失神经支配和传导速度降低的迹象。除1例患者外,所有患者的腓肠神经活检均显示轴突退变。所有患者均接受替代治疗,所有患者的临床症状和神经生理学参数均有改善。