Herrin J R, Squier C A, Rubright W C
Dows Institute of Dental Research, University of Iowa College of Dentistry, Iowa City 52242.
J Periodontol. 1987 Nov;58(11):785-8. doi: 10.1902/jop.1987.58.11.785.
The use of a periodontal home care regime has been found to induce erosive gingival lesions in some individuals. The purpose of this study was to determine which of the chemical or physical components of the technique might be responsible for the changes observed. Ten normotensive subjects were assigned to two groups. Group I subjects used a dentifrice consisting either of sodium bicarbonate and 3% hydrogen peroxide or 3% hydrogen peroxide alone; the dentifrice was removed with a 5 M NaCl irrigating solution. Group II subjects used the same dentifrices as Group I subjects, but distilled water was used as irrigant instead of 5 M NaCl. Erosive lesions of gingiva developed in all six subjects in Group I using the soda-paste dentifrice and 5 M NaCl irrigant; however, no lesions were found in Group II subjects. The use of a saturated NaCl irrigating solution appears to be injurious to gingiva, possibly as a result of the markedly hypertonic solution dehydrating the epithelium.
研究发现，采用某些牙周家庭护理方法会在一些个体中引发牙龈糜烂性病变。本研究的目的是确定该护理方法中的化学或物理成分中，哪些可能是导致观察到的这些变化的原因。10名血压正常的受试者被分为两组。第一组受试者使用由碳酸氢钠和3%过氧化氢组成的牙膏或仅使用3%过氧化氢的牙膏；用5M氯化钠冲洗液去除牙膏。第二组受试者使用与第一组相同的牙膏，但用蒸馏水代替5M氯化钠作为冲洗液。第一组中使用含小苏打牙膏和5M氯化钠冲洗液的所有6名受试者均出现了牙龈糜烂性病变；然而，第二组受试者未发现病变。使用饱和氯化钠冲洗液似乎对牙龈有害，这可能是由于该明显高渗溶液使上皮脱水所致。
