麦克尔病中的急性肾衰竭。

Acute renal failure in McArdle's disease.

作者信息

Stamos G E, Crouch T T, Wood W G, Sharma J N

出版信息

South Med J. 1979 Jan;72(1):77-9. doi: 10.1097/00007611-197901000-00022.

DOI:10.1097/00007611-197901000-00022

Abstract

A case of reversible acute renal failure in an adult with myophosphorylase deficiency (McArdle's disease) is described. Myoglobinuria, possibly abetted by intravenous urography, was incriminated as the cause of impairment of renal function.A muscle biopsy specimen contained necrotic fibers and no histochemically demonstrable phosphorylase activity. Ultrastructurally, nonspecific degenerative changes were observed.

摘要

本文描述了一例患有肌磷酸化酶缺乏症（麦卡德尔病）的成人可逆性急性肾衰竭病例。肌红蛋白尿可能因静脉肾盂造影而加重，被认为是肾功能损害的原因。肌肉活检标本含有坏死纤维，且未检测到组织化学可显示的磷酸化酶活性。超微结构观察显示非特异性退行性改变。