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用于上气道阻塞的产时宫外治疗(EXIT)。

Ex utero intrapartum treatment (EXIT) for upper airway obstruction.

作者信息

Butler Colin R, Maughan Elizabeth F, Pandya Pranav, Hewitt Richard

机构信息

aDepartment of Otolaryngology, Great Ormond Street Hospital for Children NHS Foundation TrustbFetal Medicine Unit, University College London Hospital NHS Trust, London, UK.

出版信息

Curr Opin Otolaryngol Head Neck Surg. 2017 Apr;25(2):119-126. doi: 10.1097/MOO.0000000000000343.

DOI:10.1097/MOO.0000000000000343
PMID:28267705
Abstract

PURPOSE OF REVIEW

Improvements in the antenatal diagnosis of congenital malformations have led to increased detection of fetal airway obstructing lesions, and pediatric ear, nose, and throat surgeons are increasingly involved in these cases.

RECENT FINDINGS

This article outlines the typical range of pathology seen, the logistics in providing support for anticipated deliveries and the multidisciplinary management of complex airway cases.

SUMMARY

Traditionally, difficulty in obtaining a patent airway at delivery was a major factor in the dismal prognosis of these pregnancies. The ex utero intrapartum treatment procedure, which involves controlled partial delivery of the fetus whilst maintaining placental circulation, allows various airway maneuvers to be performed to secure the airway in a controlled fashion.

摘要

综述目的

先天性畸形产前诊断的改善使得胎儿气道阻塞性病变的检出率增加,小儿耳鼻喉科医生越来越多地参与到这些病例的治疗中。

最新发现

本文概述了所见病理的典型范围、为预期分娩提供支持的相关事宜以及复杂气道病例的多学科管理。

总结

传统上,分娩时难以获得通畅气道是这些妊娠预后不良的主要因素。宫外产时治疗程序,即在维持胎盘循环的同时控制胎儿部分娩出,允许以可控方式进行各种气道操作以确保气道安全。

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1
Ex utero intrapartum treatment (EXIT) for upper airway obstruction.用于上气道阻塞的产时宫外治疗(EXIT)。
Curr Opin Otolaryngol Head Neck Surg. 2017 Apr;25(2):119-126. doi: 10.1097/MOO.0000000000000343.
2
A review of the EXIT (Ex utero Intrapartum Treatment) procedure.对EXIT(产时宫外治疗)手术的综述。
J Obstet Gynaecol. 2010 Jan;30(1):1-5. doi: 10.3109/01443610903281656.
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Operating on placental support: the ex utero intrapartum treatment procedure.基于胎盘支持进行手术:子宫外产时处理程序。
J Pediatr Surg. 1997 Feb;32(2):227-30; discussion 230-1. doi: 10.1016/s0022-3468(97)90184-6.
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Ex-utero intrapartum therapy.子宫外产时治疗。
Semin Fetal Neonatal Med. 2010 Feb;15(1):34-9. doi: 10.1016/j.siny.2009.05.007. Epub 2009 Aug 15.
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Prenatal diagnosis of obstructive head and neck masses and perinatal airway management: the ex utero intrapartum treatment procedure.梗阻性头颈部肿块的产前诊断及围产期气道管理:宫外产时治疗程序
Otolaryngol Clin North Am. 2015 Feb;48(1):191-207. doi: 10.1016/j.otc.2014.09.013.
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Prenatal diagnosis of airway compromise: EXIT (ex utero intra-partum treatment) and foetal airway surgery.气道受压的产前诊断:EXIT(产时宫外治疗)与胎儿气道手术。
Int J Pediatr Otorhinolaryngol. 2000 Jun 30;53(2):137-41. doi: 10.1016/s0165-5876(00)00323-2.
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[The multidisciplinary challenge of anesthesia for ex utero intrapartum treatment: a case report].[子宫外产时处理麻醉的多学科挑战:一例报告]
Braz J Anesthesiol. 2020 Jan-Feb;70(1):59-62. doi: 10.1016/j.bjan.2019.12.010. Epub 2020 Feb 19.
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Management of the critical airway when an EXIT procedure is not an option: A case report.当无法选择产时宫外手术时的紧急气道管理:一例病例报告。
Int J Pediatr Otorhinolaryngol. 2015 Dec;79(12):2433-7. doi: 10.1016/j.ijporl.2015.08.044. Epub 2015 Sep 10.
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Airway management on placental support (AMPS)--the anaesthetic perspective.
Anaesth Intensive Care. 2002 Oct;30(5):647-59. doi: 10.1177/0310057X0203000518.
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Immediate operative management of the fetus with airway anomalies resulting from congenital malformations.对因先天性畸形导致气道异常的胎儿进行即刻手术处理。
Semin Fetal Neonatal Med. 2016 Aug;21(4):240-5. doi: 10.1016/j.siny.2016.04.003. Epub 2016 Apr 27.

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