Brown James E, Stadnik Paul J, Stotts Larry J, Von Arx Jeffrey A
Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug;2016:6465-6468. doi: 10.1109/EMBC.2016.7592209.
Until recently, patients with active implantable medical devices (AIMDs) have been contraindicated for magnetic resonance imaging (MRI). Current efforts to demonstrate safety of these devices separate the interaction of the device and MRI into several hazards. For several of these hazards, computational human phantoms (CHPs) are used to provide conservative conditions for a risk-based analysis. This use of CHPs for the identification of conservative conditions provides a substantial benefit to the assessment of MR conditional safety over experimental techniques, as the evaluation of millions of test cases is possible in simulation, but impractical (due to economic constraints) and, in some cases, unethical for an experimental effort.
直到最近，体内植入有源医疗设备（AIMD）的患者仍被视为磁共振成像（MRI）的禁忌人群。目前为证明这些设备的安全性所做的努力，将设备与MRI的相互作用分为了几种风险。对于其中的几种风险，使用计算人体模型（CHP）来为基于风险的分析提供保守条件。使用CHP来确定保守条件，相较于实验技术，在评估MR条件安全性方面具有显著优势，因为在模拟中可以评估数百万个测试案例，但在实验中不切实际（由于经济限制），而且在某些情况下不符合伦理道德。
