Roy Sanjoy, Yoo Andrew, Yadalam Sashi, Fegelman Elliott J, Kalsekar Iftekhar, Johnston Stephen S
a Ethicon , Somerville , NJ , USA.
b Johnson & Johnson ; New Brunswick , NJ , USA.
J Med Econ. 2017 Apr;20(4):423-433. doi: 10.1080/13696998.2017.1296453. Epub 2017 Mar 8.
To compare economic and clinical outcomes between patients undergoing laparoscopic Roux-en-Y gastric bypass (LRY) or laparoscopic sleeve gastrectomy (LSG) with use of powered vs manual endoscopic surgical staplers.
Patients (aged ≥21 years) who underwent LRY or LSG during a hospital admission (January 1, 2012-September 30, 2015) were identified from the Premier Perspective Hospital Database. Use of powered vs manual staplers was identified from hospital administrative billing records. Multivariable analyses were used to compare the following outcomes between the powered and manual stapler groups, adjusting for patient and hospital characteristics and hospital-level clustering: hospital length of stay (LOS), total hospital costs, medical/surgical supply costs, room and board costs, operating room costs, operating room time, discharge status, bleeding/transfusion during the hospital admission, and 30, 60, and 90-day all-cause readmissions.
The powered and manual stapler groups comprised 9,851 patients (mean age = 44.6 years; 79.3% female) and 21,558 patients (mean age = 45.0 years; 78.0% female), respectively. In the multivariable analyses, adjusted mean hospital LOS was 2.1 days for both the powered and manual stapler groups (p = .981). Adjusted mean total hospital costs ($12,415 vs $13,547, p = .003), adjusted mean supply costs ($4,629 vs $5,217, p = .011), and adjusted mean operating room costs ($4,126 vs $4,413, p = .009) were significantly lower in the powered vs manual stapler group. The adjusted rate of bleeding and/or transfusion during the hospital admission (2.46% vs 3.22%, p = .025) was significantly lower in the powered vs manual stapler group. The adjusted rates of 30, 60, and 90-day all-cause readmissions were similar between the groups (all p > .05). Sub-analysis by manufacturer showed similar results.
This observational study cannot establish causal linkages.
In this analysis of patients who underwent LRY or LSG, the use of powered staplers was associated with better economic outcomes, and a lower rate of bleeding/transfusion vs manual staplers in the real-world setting.
比较使用电动与手动内镜手术吻合器进行腹腔镜Roux-en-Y胃旁路术(LRY)或腹腔镜袖状胃切除术(LSG)患者的经济和临床结局。
从Premier Perspective医院数据库中识别出在2012年1月1日至2015年9月30日住院期间接受LRY或LSG手术的患者(年龄≥21岁)。从医院行政计费记录中确定电动与手动吻合器的使用情况。采用多变量分析比较电动和手动吻合器组之间的以下结局,并对患者和医院特征以及医院层面的聚类进行调整:住院时间(LOS)、医院总费用、医疗/手术用品费用、食宿费用、手术室费用、手术时间、出院状态、住院期间出血/输血情况以及30、60和90天全因再入院率。
电动吻合器组和手动吻合器组分别包括9851例患者(平均年龄=44.6岁;79.3%为女性)和21558例患者(平均年龄=45.0岁;78.0%为女性)。在多变量分析中,电动和手动吻合器组的调整后平均住院LOS均为2.1天(p=0.981)。电动吻合器组的调整后平均医院总费用(12415美元对13547美元,p=0.003)、调整后平均用品费用(4629美元对5217美元,p=0.011)和调整后平均手术室费用(4126美元对4413美元,p=0.009)显著低于手动吻合器组。电动吻合器组住院期间出血和/或输血的调整率(2.46%对3.22%,p=0.025)显著低于手动吻合器组。两组之间30、60和90天全因再入院的调整率相似(所有p>0.05)。按制造商进行的亚组分析显示了相似的结果。
这项观察性研究无法建立因果联系。
在对接受LRY或LSG手术患者的这项分析中,在现实环境中,使用电动吻合器与更好的经济结局以及低于手动吻合器的出血/输血率相关。