Department of Neurology, The Johns Hopkins University, Baltimore, MD, USA.
Department of Otolaryngology-Head and Neck Surgery, The Johns Hopkins University, Baltimore, MD, USA.
J Neurol. 2017 Oct;264(Suppl 1):7-12. doi: 10.1007/s00415-017-8420-4. Epub 2017 Mar 7.
Human subjects placed in strong magnetic fields such as in an MRI scanner often feel dizzy or vertiginous. Recent studies in humans and animals have shown that these effects arise from stimulation of the labyrinth and are accompanied by nystagmus. Here, we measured the three-dimensional pattern of nystagmus using video eye tracking in five normal human subjects placed in a 7T MRI to infer which semicircular canals are activated by magnetic vestibular stimulation. We found that the nystagmus usually had a torsional as well as a horizontal component. Analysis of the relative velocities of the three eye movement components revealed that the lateral and anterior (superior) canals are the only canals activated, and by a similar amount.
人受试者置于强磁场中,如磁共振成像(MRI)扫描仪中,常常感到头晕或眩晕。最近的人体和动物研究表明,这些效应是由迷路刺激引起的,并伴有眼球震颤。在这里,我们使用视频眼动跟踪技术在五名正常人体受试者置于 7T MRI 中测量了眼球震颤的三维模式,以推断磁前庭刺激激活了哪些半规管。我们发现,眼球震颤通常具有扭转和水平分量。对三个眼球运动分量的相对速度的分析表明,外侧和前(上)管是唯一被激活的管,并且激活程度相似。