Murthy Venkatesh L, Dorbala Sharmila
Frankel Cardiovascular Center, University of Michigan, 1500 E. Medical Center Dr, Ann Arbor, MI, 48109-5873, USA.
Cardiovascular Imaging Program, Departments of Medicine and Radiology, Division of Nuclear Medicine, Department of Radiology, Brigham and Women's Hospital, 75 Francis St, Boston, MA, 02115, USA.
J Nucl Cardiol. 2017 Jun;24(3):1002-1006. doi: 10.1007/s12350-017-0836-9. Epub 2017 Mar 7.
Exercise results in increased left ventricular contractility in normal individuals. Similar changes can also be seen with vasodilator stress. This article discusses the physiologic basis of these changes as well as reviews the clinical data supporting the use of these parameters for diagnostic and prognostic evaluation. Methodologic limitations as well as other concomitant pathologic processes which may confound interpretation of stress-induced changes in LVEF are also reviewed.
运动可使正常个体的左心室收缩力增强。血管扩张剂负荷试验时也可观察到类似变化。本文讨论了这些变化的生理基础,并综述了支持将这些参数用于诊断和预后评估的临床数据。还综述了方法学局限性以及可能混淆对负荷诱导的左心室射血分数变化解释的其他伴随病理过程。