Schild H, Kreitner K F, Thelen M, Grönninger J, Weber M, Börner N, Störkel J, Eissner D
Institut für Klinische Strahlenkunde, Klinikum der Johannes-Gutenberg-Universität Mainz.
Rofo. 1987 Dec;147(6):612-8. doi: 10.1055/s-2008-1048709.
Analysis of 930 patients with focal nodular hyperplasia of the liver (FNH), including 23 seen by the authors, showed the following results: 82.2% of patients were female, 37.8% of these had taken female steroidal hormones. There was no preference for a particular lobe of the liver. 57.7% of FNH were subcapsular, 33.7% were intrahepatic and 8.8% were pedunculated. Average size was 5.9 cm, 80.8% of the patients were asymptomatic. In 93.5% (115 out of 123) a space-occupying lesion in the liver could be demonstrated by sonography. In 13%, second or multiple tumours were missed by sonography. CT without enhancement demonstrated FNH in 90.4% (94 out of 104 patients). A rapid, marked increase in density after contrast was seen in 64 out of 68 lesions (94.1%). Colloid scintigraphy showed normal uptake in 34.9% of patients. Hepato-biliary functional scintigraphy demonstrated 32 out of 35 lesions (91.4%). In 97.3% (183 out of 188) FNH was demonstrated by angiography, in 95.4% as a highly vascular tumour.
对930例肝局灶性结节性增生（FNH）患者（包括作者所诊治的23例）的分析结果如下：82.2%的患者为女性，其中37.8%曾服用过女性甾体激素。FNH在肝脏各叶分布无明显差异。57.7%的FNH位于肝包膜下，33.7%位于肝内，8.8%有蒂。平均大小为5.9 cm，80.8%的患者无症状。93.5%（123例中的115例）患者肝脏内的占位性病变可通过超声检查显示。13%的患者超声检查漏诊了第二个或多个肿瘤。平扫CT显示104例患者中有90.4%（94例）为FNH。68个病灶中有64个（94.1%）在增强扫描后密度迅速、显著增加。胶体闪烁扫描显示34.9%的患者摄取正常。肝胆功能闪烁扫描显示35个病灶中有32个（91.4%）。血管造影显示97.3%（188例中的183例）为FNH，95.4%表现为富血管肿瘤。
