锝 Tc 99m 二巯基丁二酸肾闪烁显像：在患有多囊性肾发育不良的新生儿中的临床应用。

Renal scintigraphy with technetium Tc 99m succimer: clinical utility in newborns with cystic renal dysplasia.

作者信息

Copely D J, Smith R, Murakami M E

机构信息

Department of Radiology, University Hospital of Jacksonville, Fla.

出版信息

South Med J. 1988 Jan;81(1):99-100. doi: 10.1097/00007611-198801000-00025.

DOI:10.1097/00007611-198801000-00025

PMID:2827323

Abstract

We have presented the case of a neonate with bilateral cystic renal dysplasia and normal pulmonary development, in whom technetium Tc 99m succimer scintigraphy demonstrated absence of normal renal cortical tubular tissue and correctly predicted that life-sustaining renal function would not occur. Since renal uptake of this radioactive agent depends on the functional mass of cortical tubular tissue, and the cystic dysplasias are characterized by abnormal dysplastic renal ductal and tubular tissue, this imaging agent can provide important prognostic information concerning renal function in these patients.

摘要

我们报告了一例患有双侧囊性肾发育不良但肺部发育正常的新生儿病例，在该病例中，锝 Tc 99m 二巯基丁二酸闪烁显像显示不存在正常的肾皮质肾小管组织，并正确预测不会出现维持生命的肾功能。由于这种放射性药物的肾脏摄取取决于皮质肾小管组织的功能量，且囊性发育不良的特征是肾导管和肾小管组织发育异常，这种显像剂可以提供有关这些患者肾功能的重要预后信息。