儿童高血压。锝 Tc 99m 二巯基丁二酸在肾病筛查中的疗效提高。

Hypertension in children. Increased efficacy of technetium Tc 99m succimer in screening for renal disease.

作者信息

Rosen P R, Treves S, Ingelfinger J

出版信息

Am J Dis Child. 1985 Feb;139(2):173-7. doi: 10.1001/archpedi.1985.02140040075031.

DOI:10.1001/archpedi.1985.02140040075031

Abstract

Renal scintigraphy with technetium Tc 99m succimer (DMSA) and technetium Tc 99m pentetate (DTPA) was used to study 80 hypertensive pediatric and adolescent patients. Renal abnormalities such as asymmetry of function, size, or shape were identified in 13 patients. Both excretory urography and technetium Tc 99m pentetate studies were successful in detecting 54% of the abnormalities in patients studied; technetium Tc 99m succimer identified 92%. The accuracy of the latter was 96%, with a specificity of 97%. The ability of technetium Tc 99m succimer renal scintigraphy to identify accurately the presence or absence of renal abnormalities warrants its inclusion in the initial examination of pediatric and adolescent patients with hypertension.

摘要

采用锝 Tc 99m 二巯基丁二酸（DMSA）和锝 Tc 99m 喷替酸盐（DTPA）肾闪烁显像术对 80 例高血压儿科和青少年患者进行了研究。在 13 例患者中发现了肾功能、大小或形态不对称等肾脏异常情况。排泄性尿路造影和锝 Tc 99m 喷替酸盐研究在检测所研究患者的异常情况方面成功率均为 54%；锝 Tc 99m 二巯基丁二酸识别出了 92%的异常情况。后者的准确率为 96%，特异性为 97%。锝 Tc 99m 二巯基丁二酸肾闪烁显像术准确识别肾脏异常情况有无的能力，使其有必要纳入高血压儿科和青少年患者的初始检查中。