Gardner Tyler J, Prahlow Joseph A
Western Michigan University Homer Stryker M.D. School of Medicine, Department of Pathology, United States.
Western Michigan University Homer Stryker M.D. School of Medicine, Department of Pathology, United States.
J Forensic Leg Med. 2017 Apr;47:35-38. doi: 10.1016/j.jflm.2017.02.007. Epub 2017 Feb 28.
Cerebral artery aneurysm rupture is usually associated with significant subarachnoid hemorrhage; however, there are rare cases where there is a lack of hemorrhage into the subarachnoid space. While subdural hemorrhage can occur with ruptured aneurysms, isolated subdural hemorrhage is more often associated with trauma. In this case, a 51-year-old obese woman, who recently visited an Urgent Care Center for elevated blood pressure, was found dead roughly a month later. She had been complaining of headaches, and received medication for her blood pressure at the visit. A medicolegal autopsy revealed that the cause of death was determined to be a ruptured cerebral artery berry aneurysm of the right anterior cerebral artery, with a contributing underlying cause of hypertensive and atherosclerotic cardiovascular disease. There was significant subdural hemorrhage overlying the right cerebrum. Subarachnoid hemorrhage was present only minimally and in a patchy distribution, with virtual absence of basilar hemorrhage. An additional unruptured aneurysm was found in the left common carotid artery before the bifurcation. There was cardiomegaly (510 gm), and mild to moderate atherosclerosis in multiple vessels. The classic clinical presentation of a ruptured cerebral artery berry aneurysm involves the sudden onset of an excruciating headache. While angiography provides the most conclusive image-based antemortem evidence of an aneurysm, CT scans are used frequently in an emergency setting to identify basilar subarachnoid hemorrhage, a very common associated finding, thus allowing for a diagnosis of probable ruptured aneurysm. Depending on the circumstances of a given case, the presence of subdural hemorrhage with absence of subarachnoid hemorrhage on CT scan may suggest a different underlying process, such as trauma. The presented case serves to remind clinicians that ruptured berry aneurysms do not always produce significant subarachnoid hemorrhage.
脑动脉动脉瘤破裂通常伴有大量蛛网膜下腔出血;然而,也有罕见情况,蛛网膜下腔没有出血。虽然动脉瘤破裂时可发生硬膜下出血,但孤立性硬膜下出血更常与外伤有关。在本病例中,一名51岁的肥胖女性,近期因血压升高前往紧急护理中心就诊,大约一个月后被发现死亡。她一直抱怨头痛,就诊时接受了降压治疗。法医尸检显示,死亡原因是右大脑前动脉的脑动脉浆果状动脉瘤破裂,潜在的促成因素是高血压和动脉粥样硬化性心血管疾病。右大脑上方有大量硬膜下出血。蛛网膜下腔出血仅少量存在且呈斑片状分布,基底出血几乎没有。在左颈总动脉分叉前发现了一个额外的未破裂动脉瘤。有心脏肥大(510克),多支血管有轻度至中度动脉粥样硬化。脑动脉浆果状动脉瘤破裂的典型临床表现是突发剧烈头痛。虽然血管造影提供了基于图像的最确凿的动脉瘤生前证据,但CT扫描在紧急情况下经常用于识别基底蛛网膜下腔出血,这是一种非常常见的相关发现,从而有助于诊断可能破裂的动脉瘤。根据具体病例情况,CT扫描显示有硬膜下出血而无蛛网膜下腔出血可能提示不同的潜在病因,如外伤。本病例提醒临床医生,浆果状动脉瘤破裂并不总是导致大量蛛网膜下腔出血。