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幻觉的发生和模态共现与精神分裂症谱系障碍。

Occurrence and co-occurrence of hallucinations by modality in schizophrenia-spectrum disorders.

机构信息

Department of Psychiatry, Trinity College Dublin, Ireland.

Department of Psychology, Leeds Trinity University, Leeds, UK.

出版信息

Psychiatry Res. 2017 Jun;252:154-160. doi: 10.1016/j.psychres.2017.01.102. Epub 2017 Feb 24.

DOI:10.1016/j.psychres.2017.01.102
PMID:28273630
Abstract

It is not only unclear why hallucinations in schizophrenia occur with different prevalence by modality, but also to what extent they do. Reliable prevalence estimates of hallucinations by modality in schizophrenia are currently lacking, particularly for non-auditory hallucinations. Studies have also tended to report lifetime, not point prevalence by modality. This study assessed the prevalence and co-occurrence of hallucinations, for both lifetime and point prevalence, across the auditory, visual, olfactory, and tactile modalities, in people diagnosed with chronic schizophrenia-spectrum disorders in Ireland (N=693) and Australia (N=218). Lifetime prevalence was 64-80% auditory, 23-31% visual, 9-19% tactile, and 6-10% olfactory. Past month prevalence was 23-27% auditory, 5-8% visual, 4-7% tactile, and 2% olfactory. The majority of participants had only hallucinated in one modality, with this nearly always being the auditory. Approximately one-third had hallucinated in two modalities, most commonly the auditory and visual. Most currently hallucinating patients also hallucinated in a single modality, again, nearly always the auditory. Whereas 30-37% of patients with lifetime auditory hallucinations had experienced visual hallucinations, 83-97% of patients with experience of visual hallucinations had experienced auditory hallucinations. These findings help delineate the modality distribution of hallucinations in schizophrenia, and provide an explanatory target for theoretical models.

摘要

幻觉在精神分裂症中以不同的模态出现,其流行率不仅不清楚,而且其程度也不清楚。目前,精神分裂症中各种模态的幻觉可靠流行率估计值,特别是非听觉幻觉,目前还很缺乏。研究也倾向于报告终生而非模态的现患率。本研究在爱尔兰(N=693)和澳大利亚(N=218)诊断为慢性精神分裂症谱系障碍的人群中,评估了听觉、视觉、嗅觉和触觉模态的幻觉终生和现患率的患病率和共病。终生患病率为听觉 64-80%,视觉 23-31%,触觉 9-19%,嗅觉 6-10%。过去一个月的患病率为听觉 23-27%,视觉 5-8%,触觉 4-7%,嗅觉 2%。大多数参与者仅在一种模态中出现幻觉,且几乎总是听觉。大约三分之一的人在两种模态中出现幻觉,最常见的是听觉和视觉。大多数目前有幻觉的患者也在单一模态中出现幻觉,再次,几乎总是听觉。有终生听觉幻觉的患者中,有 30-37%有视觉幻觉,有视觉幻觉经历的患者中,有 83-97%有听觉幻觉。这些发现有助于描绘精神分裂症中幻觉的模态分布,并为理论模型提供解释目标。

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