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伊朗的癌症研究重点与差距:1997年至2014年间癌症负担对癌症研究产出的影响。

Cancer research priorities and gaps in Iran: the influence of cancer burden on cancer research outputs between 1997 and 2014.

作者信息

Majidi A, Salimzadeh H, Beiki O, Delavari F, Majidi S, Delavari A, Malekzadeh R

机构信息

Digestive Oncology Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Karolinska Institutet, Stockholm, Sweden; Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

Public Health. 2017 Mar;144:42-47. doi: 10.1016/j.puhe.2016.11.002. Epub 2016 Dec 30.

Abstract

OBJECTIVES

As a developing country, Iran is experiencing the increasing burden of cancers, which are currently the third leading cause of mortality in Iran. This study aims to demonstrate that cancer research in Iran concentrates on the cancer research priorities based on the global burden of disease (GBD) reports.

STUDY DESIGN

Descriptive evaluation of all cancers disability-adjusted life years (DALYs) was performed using GBD data. Also a comprehensive search was conducted using cancer-associated keywords to obtain all cancer-related publications from Iran, indexed in Web of Science.

METHOD

Multiple regression analysis and correlation coefficients (R) were used to evaluate the possible associations between cancer research publications and GBD.

RESULTS

During 1996-2014, the majority of cancer-related publications in Iran focused on breast cancer, leukaemia and stomach cancer, respectively. This study found hypothetical correlations between cancer publications in Iran in line with the burden of cancer as reported by GBD. Particularly, correlations between years lived with disability (YLD) and cancer-related publications were more obvious.

CONCLUSION

This study introduces a new outline in setting cancer research priorities in the region.

摘要

目标

作为一个发展中国家,伊朗正面临着日益加重的癌症负担,癌症目前是伊朗第三大死因。本研究旨在证明伊朗的癌症研究集中于基于全球疾病负担(GBD)报告的癌症研究重点。

研究设计

使用GBD数据对所有癌症伤残调整生命年(DALYs)进行描述性评估。还使用与癌症相关的关键词进行了全面检索,以获取来自伊朗且被科学引文索引收录的所有癌症相关出版物。

方法

采用多元回归分析和相关系数(R)来评估癌症研究出版物与GBD之间的可能关联。

结果

在1996 - 2014年期间,伊朗大多数癌症相关出版物分别聚焦于乳腺癌、白血病和胃癌。本研究发现伊朗癌症出版物与GBD报告的癌症负担之间存在假设的相关性。特别是,伤残调整生命年(YLD)与癌症相关出版物之间的相关性更为明显。

结论

本研究为该地区确定癌症研究重点引入了一个新的框架。

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