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气管插管后气管食管瘘的手术及围手术期管理:病例系列分析

Surgery and perioperative management for post-intubation tracheoesophageal fistula: case series analysis.

作者信息

Puma Francesco, Vannucci Jacopo, Santoprete Stefano, Urbani Moira, Cagini Lucio, Andolfi Marco, Potenza Rossella, Daddi Niccolò

机构信息

Department of Thoracic Surgery, University of Perugia Medical School, Perugia, Italy.

Thoracic Surgery Unit, Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum, University of Bologna, Bologna, Italy.

出版信息

J Thorac Dis. 2017 Feb;9(2):278-286. doi: 10.21037/jtd.2017.02.17.

Abstract

BACKGROUND

Post-intubation tracheoesophageal fistula (PITEF) is an often mistreated, severe condition. This case series reviewed for both the choice and timing of surgical technique and outcome PITEF patients.

METHODS

This case series reviewed ten consecutive patients who had undergone esophageal defect repair and airway resection/reconstruction between 2000 and 2014. All cases were examined for patients: general condition, medical history, preparation to surgery, diagnostic work-up, timing of surgery and procedure, fistula size and site, ventilation type, nutrition, post-operative course and complications.

RESULTS

All patients were treated according to Grillo's technique. Overall, 6/10 patients had undergone a preliminary period of medical preparation. Additionally, 3 patients had already had a tracheostomy, one had had a gastrostomy and 4 had both. One patient had a Dumon stent with enlargement of the fistula. Concomitant tracheal stenosis had been found in 7 patients. The mean length of the fistulas was 20.5 mm (median 17.5 mm; range, 8-45 mm), at a median distance from the glottis of 43 mm (range, 20-68 mm). Tracheal resection was performed in all ten cases. The fistula was included in the resection in 6 patients, while it was excluded in the remaining 4 due to their distance. Post-repair tracheotomy was performed in 3 patients. The procedure was performed in 2 ventilated patients. Morbidity related to fistula and anastomosis was recorded in 3 patients (30%), with one postoperative death (10%); T-Tube placement was necessary in 3 patients, with 2/3 decannulations after long-stenting. Definitive PITEF closure was obtained for all patients. At 5-year follow-up, the 9 surviving patients had no fistula-related morbidity.

CONCLUSIONS

Primary esophageal closure with tracheal resection/reconstruction seemed to be effective treatment both short and long-term. Systemic conditions, mechanical ventilation, detailed preoperative assessment and appropriate preparation were associated with outcome. Indeed, the 3 patients who had received T-Tube recovered from anastomotic complications.

摘要

背景

气管插管后气管食管瘘(PITEF)是一种常被误诊的严重病症。本病例系列回顾了PITEF患者手术技术的选择、时机及预后情况。

方法

本病例系列回顾了2000年至2014年间连续接受食管缺损修复及气道切除/重建手术的10例患者。对所有病例的患者进行如下检查:一般状况、病史、术前准备、诊断性检查、手术时机及步骤、瘘口大小及位置、通气类型、营养状况、术后病程及并发症。

结果

所有患者均按照格里洛技术进行治疗。总体而言,10例患者中有6例经历了一段术前药物准备期。此外,3例患者已行气管切开术,1例已行胃造口术,4例两者均有。1例患者置入了杜蒙支架,瘘口增大。7例患者伴有气管狭窄。瘘口平均长度为20.5毫米(中位数17.5毫米;范围8 - 45毫米),距声门的中位距离为43毫米(范围20 - 68毫米)。10例患者均行气管切除术。6例患者的瘘口被纳入切除范围,其余4例因距离原因未被纳入。3例患者术后行气管切开术。该手术在2例通气患者中进行。3例患者(30%)记录到与瘘口和吻合口相关的并发症,1例术后死亡(10%);3例患者需要放置T形管,其中2/3在长期置管后拔管。所有患者均实现了PITEF的最终闭合。在5年随访时,9例存活患者无瘘口相关并发症。

结论

气管切除/重建联合一期食管闭合术似乎是一种短期和长期均有效的治疗方法。全身状况、机械通气、详细的术前评估及适当的准备与预后相关。事实上,接受T形管治疗的3例患者从吻合口并发症中康复。

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