Tazi-Mezalek Rachid, Musani Ali I, Laroumagne Sophie, Astoul Philippe J, D'Journo Xavier B, Thomas Pascal A, Dutau Hervé
Thoracic Oncology, Pleural Diseases and Interventional Pulmonology Department, North University Hospital, Marseille, France.
Interventional Pulmonology, Pulmonary and Critical Care Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Respirology. 2016 Nov;21(8):1452-1458. doi: 10.1111/resp.12853. Epub 2016 Jul 21.
Iatrogenic tracheal injury (ITI) is a rare yet severe complication of endotracheal tube (ETT) placement or tracheostomy. ITI is suspected in patients with clinical and/or radiographic signs or inefficient mechanical ventilation (MV) following these procedures. Bronchoscopy is used to establish a definitive diagnosis.
We conducted a retrospective, single-centre chart review of 35 patients between 2004 and 2014. Depending on the nature and location of ITI and need for MV, patients were triaged to surgical repair, endoscopic management with airway stents or conservative treatment consisting of ETT or tracheotomy cannula (TC) placement distal to the wound and bronchoscopic surveillance.
Three of the four patients (11.43%) presenting with tracheoesophageal fistula (TEF) underwent surgery. Seven patients (20%) who did not require MV underwent endoscopic surveillance. Of the 24 ventilated patients (68.57%), 7 with ITI in the lower trachea were treated with silicone Y-stent (ETT or TC was placed inside the stent) and 17 patients with ITI in the upper trachea were managed by placing ETT or TC cuff distal to the injury. Overall management success, defined as complete healing of the ITI, was seen in 88.57% of patients. Four patients (11.43%) died of non-ITI-related comorbidities.
Conservative management should be considered in non-ventilated patients with ITI and when ITI is located in the upper trachea of ventilated patients where ETT or TC bypasses the injury. Airway stenting should be considered in ventilated patients with ITI located in the lower trachea. Surgery should be reserved for TEF and conservative and endoscopic management failure.
医源性气管损伤(ITI)是气管插管(ETT)置入或气管切开术罕见但严重的并发症。在这些操作后出现临床和/或影像学体征或机械通气(MV)效果不佳的患者中怀疑有ITI。支气管镜检查用于明确诊断。
我们对2004年至2014年间的35例患者进行了一项回顾性单中心病历审查。根据ITI的性质和位置以及MV的需求,将患者分类为手术修复、气道支架内镜治疗或保守治疗,保守治疗包括在伤口远端放置ETT或气管切开套管(TC)并进行支气管镜监测。
4例出现气管食管瘘(TEF)的患者中有3例(11.43%)接受了手术。7例不需要MV的患者(20%)接受了内镜监测。在24例接受通气的患者(68.57%)中,7例下气管ITI患者采用硅胶Y形支架治疗(ETT或TC置于支架内),17例上气管ITI患者通过在损伤远端放置ETT或TC袖带进行处理。总体治疗成功率定义为ITI完全愈合,见于88.57%的患者。4例患者(11.43%)死于与ITI无关的合并症。
对于非通气的ITI患者以及通气患者中ITI位于上气管且ETT或TC绕过损伤部位的情况,应考虑保守治疗。对于ITI位于下气管的通气患者,应考虑气道支架置入。手术应保留用于TEF以及保守和内镜治疗失败的情况。