Aluclu Mustafa Arif, Bati Fatih, Kekilli Ersoy
Department of Pediatrics, Yenisehir Hospital, Mersin, Turkey.
Department of Nuclear Medicine, Malatya State Hospital, Malatya, Turkey.
North Clin Istanb. 2017 Jan 25;3(3):201-208. doi: 10.14744/nci.2016.95866. eCollection 2016.
Osteoporosis is progressive metabolic bone disease that decreases bone density and features deterioration of bone structure. Dual-energy X-ray absorptiometry (DXA) is commonly used and reliable method to measure bone mineral density (BMD). Aim of this study was to determine normal ranges of BMD in left proximal tibia.
Fifty-five females were included in this study. BMD was measured at the lumbar spine and the left proximal tibia using DXA. BMD value of subregions in the left proximal tibia was significantly correlated with BMD value of the total lumbar spine (r=0.111-0.766). New average BMD values of the left proximal tibia were calculated according to age using linear regression formula, leading to average BMD value for the total lumbar spine (L1-L4) in normal population. New simulated T-scores for proximal subregions of the tibia were then calculated.
T-scores for proximal subregions were not different from T-scores of total lumbar spine (p>0.05).
It was concluded that proximal tibia is an ideal region for measurement of BMD in osteoporosis.
骨质疏松症是一种进行性代谢性骨病,会降低骨密度并导致骨结构恶化。双能X线吸收法(DXA)是常用且可靠的测量骨矿物质密度(BMD)的方法。本研究的目的是确定左胫骨近端BMD的正常范围。
本研究纳入了55名女性。使用DXA测量腰椎和左胫骨近端的BMD。左胫骨近端各亚区域的BMD值与整个腰椎的BMD值显著相关(r = 0.111 - 0.766)。根据年龄使用线性回归公式计算左胫骨近端的新平均BMD值,得出正常人群中整个腰椎(L1 - L4)的平均BMD值。然后计算胫骨近端亚区域的新模拟T值。
近端亚区域的T值与整个腰椎的T值无差异(p>0.05)。
得出结论,胫骨近端是骨质疏松症中测量BMD的理想区域。