Cahir Caitriona, Dombrowski Stephan U, Kennedy M John, Sharp Linda, Bennett Kathleen
a Division of Population Health Sciences , Royal College of Surgeons in Ireland , Dublin , Ireland.
b Division of Psychology , University of Stirling , Stirling , Scotland.
Psychol Health. 2017 Oct;32(10):1308-1326. doi: 10.1080/08870446.2017.1296151. Epub 2017 Feb 28.
Taking adjuvant hormonal therapy for 5-10 years is recommended to prevent breast cancer recurrence in those with oestrogen positive disease. Despite proven clinical efficacy many women do not take their hormonal therapy as prescribed. This study reports the development and initial validation of a questionnaire measuring the behavioural determinants of hormonal therapy medication taking behaviour (MTB) based on the theoretical domains framework (TDF).
Women with Stage I-III breast cancer (N = 223) completed the questionnaire based on the TDF. The TDF is an integrative framework consisting of 14 domains of behaviour change determinants to inform intervention design.
Items were developed from previous research, in-depth patient interviews and consultation with health professionals. Confirmatory factor analysis (CFA) was undertaken to generate the model of best fit.
The final questionnaire consisted of eight domains and CFA produced a reasonable fit (χ(810) = 942, p < .001; RMSEA = .03; CFI = .93 and WRMR = .91) as well as internal consistency (r = .16 to .64). There were adequate levels of discriminant validity for the majority of the domains.
A TDF-based measure of the behavioural determinants of MTB was developed. Further research is needed to confirm the reliability and validity of this measure.
对于雌激素受体阳性的乳腺癌患者，推荐进行5至10年的辅助激素治疗以预防癌症复发。尽管激素治疗的临床疗效已得到证实，但许多女性并未按医嘱进行激素治疗。本研究报告了一份基于理论领域框架（TDF）的问卷的开发及初步验证，该问卷用于测量激素治疗服药行为（MTB）的行为决定因素。
I至III期乳腺癌女性患者（N = 223）完成了基于TDF的问卷。TDF是一个综合框架，由14个行为改变决定因素领域组成，为干预设计提供依据。
条目基于先前研究、深入的患者访谈以及与健康专业人员的咨询而制定。进行验证性因子分析（CFA）以生成最佳拟合模型。
最终问卷包含八个领域，CFA显示拟合度合理（χ(810) = 942，p <.001；RMSEA =.03；CFI =.93；WRMR =.91）且具有内部一致性（r =.16至.64）。大多数领域具有足够的区分效度。
开发了一种基于TDF的MTB行为决定因素测量方法。需要进一步研究以确认该测量方法的可靠性和有效性。
