在动物模型中使用克氏针与自体纤维蛋白胶治疗股骨远端关节内骨折的比较。

Comparison of healing intra-articular fracture of distal femur using a Kirschner wire and autologous fibrin glue in an animal model.

作者信息

Azarpira Mohammad R, Vazani Kasra, Ayatollahi Maryam, Azarpira Negar, Kaviani Maryam

机构信息

aDepartment of Orthopedics bBone and Joint Diseases Research Center cTransplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

J Pediatr Orthop B. 2017 Sep;26(5):454-457. doi: 10.1097/BPB.0000000000000444.

DOI:10.1097/BPB.0000000000000444

PMID:28277417

Abstract

UNLABELLED

Considering different surgical techniques for the fixation of osteochondral intra-articular fracture, the present study aimed to compare the efficacy of autologous fibrin glue and Kirschner wire (KW) on an osteochondral fracture in the left lateral condyle of Dutch rabbits with a control group. After 6 weeks, macroscopic and microscopic evaluation showed that autologous fibrin glue is easier and faster with a higher number of bone trabecula (P<0.05), whereas the healing rate and cellularity of the healing site were not different between the two groups (KW and glue). The use of autologous fibrin glue can be an alternative to KW fixation in the fixation of osteochondral fractures.

LEVEL OF EVIDENCE

Level II.

摘要

未标记

考虑到用于固定关节内骨软骨骨折的不同手术技术，本研究旨在比较自体纤维蛋白胶和克氏针（KW）对荷兰兔左外侧髁骨软骨骨折的疗效，并与对照组进行比较。6周后，宏观和微观评估显示，自体纤维蛋白胶操作更简便、速度更快，骨小梁数量更多（P<0.05），而两组（KW组和纤维蛋白胶组）愈合部位的愈合率和细胞密度无差异。在骨软骨骨折固定中，使用自体纤维蛋白胶可替代KW固定。