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腭裂修复术后成人的生活质量:两种技术的比较

Adult Quality of Life Post Cleft Palate Repair: A Comparison of Two Techniques.

作者信息

Skladman Rachel, Grames Lynn Marty, Skolnick Gary, Nguyen Dennis C, Naidoo Sybill D, Patel Kamlesh B, Marsh Jeffrey L, Woo Albert S

机构信息

*Washington University School of Medicine in St Louis †St Louis Children's Hospital ‡Kids Plastic Surgery, St Louis, MO §Alpert School of Medicine, Brown University, Providence, RI.

出版信息

J Craniofac Surg. 2017 Jun;28(4):909-914. doi: 10.1097/SCS.0000000000003526.

Abstract

BACKGROUND AND PURPOSE

In 1989, the Cleft Palate-Craniofacial Journal published the first randomized prospective cleft surgery study, comparing the Kriens intravelar veloplasty (IVV) with a non-IVV 2-flap repair. Results in that and follow-up publications yielded no difference between the 2 groups for need for secondary velopharyngeal management. The subjects have now reached adulthood. This study was designed to ask: Is there any difference between the groups in the outcomes that multidisciplinary team care addresses: speech intelligibility, facial growth, breathing while awake and asleep, attainment of education, and long-term socioeconomic status?

METHODS

Enrollees from the original published study were invited to participate in a survey. Subjects responded to questions about speech therapy and speech satisfaction, additional surgery, breathing patterns, sleep quality/sleep disorder, and dental occlusion. Demographic information, information on education level, profession, and socio-economic status were queried. Student t test and Fisher exact test were used to compare results.

RESULTS

Forty-two of the original 200 patients (20 Kriens IVV and 19 non-IVV) chose to participate. Average age at survey was 25 ± 3 years. Analysis yielded no difference between the 2 respondent groups for need for secondary velopharyngeal management. There were no differences in speech outcome and satisfaction (8 questions, 0.30 < P < 0.97), sleep concerns (3 questions, 0.16 < P < 0.39), and dental occlusion (P = 0.69). Equivalent proportions of the 2 groups had been in speech therapy (P = 0.22). There was no difference in education attainment of the 2 groups (P = 0.26).

CONCLUSIONS

The original randomized prospective trial suggested that there was no difference between the 2 surgery types in need for secondary velopharyngeal management. This long-term survey study on the same group of patients suggests that in young adulthood, the 2 groups have similar outcomes in terms of education, career choice, speech satisfaction, dental occlusion, and sleep disorder.

摘要

背景与目的

1989年,《腭裂-颅面外科杂志》发表了首项腭裂手术随机前瞻性研究,比较了克林斯腭内肌成形术(IVV)与非IVV双瓣修复术。该研究及后续出版物的结果显示,两组在二次腭咽管理需求方面无差异。如今,这些受试者已成年。本研究旨在探讨:在多学科团队护理所关注的结果方面,两组之间是否存在差异,这些结果包括言语清晰度、面部生长、清醒和睡眠时的呼吸、教育程度以及长期社会经济地位?

方法

邀请原始发表研究的参与者参加一项调查。受试者回答了有关言语治疗和言语满意度、额外手术、呼吸模式、睡眠质量/睡眠障碍以及牙合的问题。询问了人口统计学信息、教育水平、职业和社会经济地位信息。采用学生t检验和费舍尔精确检验来比较结果。

结果

原始200名患者中有42名(20名克林斯IVV患者和19名非IVV患者)选择参与。调查时的平均年龄为25±3岁。分析结果显示,两组在二次腭咽管理需求方面无差异。在言语结果和满意度(8个问题,0.30 < P < 0.97)、睡眠问题(3个问题,0.16 < P < 0.39)以及牙合方面(P = 0.69)均无差异。两组接受言语治疗的比例相当(P = 0.22)。两组的教育程度无差异(P = 0.26)。

结论

最初的随机前瞻性试验表明,两种手术类型在二次腭咽管理需求方面无差异。这项针对同一组患者的长期调查研究表明,在青年成年期,两组在教育、职业选择、言语满意度、牙合和睡眠障碍方面的结果相似。

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