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评估Metha®短柄对全髋关节置换术中假体周围骨重塑的影响:48个月时的结果

Evaluation of the Effects of the Metha® Short Stem on Periprosthetic Bone Remodelling in Total Hip Arthroplasties: Results at 48 Months.

作者信息

Parchi Paolo D, Ciapini Gianluca, Castellini Iacopo, Mannucci Claudia, Nucci Anna Maria, Piolanti Nicola, Maffei Silvia, Lisanti Michele

机构信息

1st Orthopedic Division, Department of Translational Research and New Technology in Medicine and Surgery, University of Pisa, Pisa, Italy.

Institute of Clinical Physiology, National Research Council, Pisa, Italy.

出版信息

Surg Technol Int. 2017 Jul 25;30:346-351.

Abstract

INTRODUCTION

Total hip arthroplasty is one of the most performed procedures in orthopaedic surgery. Implantation of a prosthesis determines changes in the distribution of loads on the host bone, and this phenomenon, known as stress shielding, is related to the biomechanical characteristics of the implant. Usually stress shielding involves the proximal portion of the femur by reducing the mechanical strength and ability to withstand the transmitted loads. The aim of our study is to demonstrate how the use of a short hip stem reduces the stress shielding phenomenon to the proximal femur.

MATERIALS AND METHODS

The study analyzed 20 patients undergoing hip prosthesis surgery with a short stem (Metha<, B. Braun Medical, Inc., Bethlehem, Pennsylvania) at the Ist Orthopaedic Division of Pisa University (between December 2008 and January 2010). Each patient was subjected to analysis of periprosthetic bone mineral density by a bone densitometry (dual emission X-ray absorptiometry [DEXA] with the metal removal software) at 0, 6, 12, 18, 24, and 36 months, following a protocol based on the evaluation of the changes of bone density in the seven Gruen zones.

RESULTS

We recorded minimal changes in bone mineral density (BMD) at the level of the greater trochanter (-1.44%) and at the level of the calcar (-3.7%). BMD increased significantly after four years at the level of the lateral distal regions (R2 +9.6% - R3 + 12.4%) and at the level of the distal medial regions (R5 + 8.2% - R6 + 13.1%). We compared the results obtained with the literature data at 12 and 24 months with the same stem (Metha<). At 12 months follow up, we did not see a significant difference between our data and the data published in the literature. However, after 48 months of follow-up, we recorded significant differences in the curves of periprosthetic bone reabsorption at the level of the greater trochanter (Zone 1) and at the level of the calcar (Zone 7).

DISCUSSION

The data obtained from our study are in agreement with other studies in the literature, which demonstrates how the use of short stems preserves the metaphyseal bone stock at the level of the proximal femur, reducing the stress shielding phenomenon. From our data, obtained at 24 months and confirmed at 36, stress shielding seems to minimally occur at the level of the calcar. At the level of the great trochanter, we saw a good load distribution that maintained the baseline BMD; these data are in opposition to the literature data that showed a high increase of BMD at the level of the calcar (+12.9%) and a decrease at the level of the great trochanter. From the analysis of the radiographic images of our cases, and of the cases published with the same stem, these differences in load transfer encountered between the great trochanter and the calcar seems to be related to the level of the femoral neck osteotomy and the consequent stem position (varus/valgus).

CONCLUSION

We conclude that the amount of periprostetic bone reabsorption around the Metha< stem seems to be strictly related to the surgical technique and the final implant position.

摘要

引言

全髋关节置换术是骨科手术中实施最多的手术之一。假体植入会导致宿主骨上负荷分布发生变化,这种被称为应力遮挡的现象与植入物的生物力学特性有关。通常,应力遮挡通过降低机械强度和承受传递负荷的能力,累及股骨近端部分。我们研究的目的是证明使用短柄髋关节假体如何减少股骨近端的应力遮挡现象。

材料与方法

本研究分析了20例在比萨大学第一骨科接受短柄(Metha<,B. Braun Medical, Inc., Bethlehem, Pennsylvania)髋关节假体手术的患者(2008年12月至2010年1月期间)。按照基于评估七个Gruen区骨密度变化的方案,在术后0、6、12、18、24和36个月,通过骨密度测定法(采用金属去除软件的双能X线吸收法[DEXA])对每位患者进行假体周围骨密度分析。

结果

我们记录到大转子水平的骨矿物质密度(BMD)变化极小(-1.44%),股骨矩水平变化也极小(-3.7%)。四年后,外侧远端区域(R2 +9.6% - R3 + 12.4%)和内侧远端区域(R5 + 8.2% - R6 + 13.1%)的BMD显著增加。我们将在12个月和24个月时使用同一假体柄(Metha<)获得的结果与文献数据进行了比较。在12个月随访时,我们的数据与文献中发表的数据之间未发现显著差异。然而,在48个月随访后,我们记录到大转子(1区)和股骨矩(7区)水平的假体周围骨吸收曲线存在显著差异。

讨论

我们研究获得的数据与文献中的其他研究一致,表明使用短柄假体可保留股骨近端干骺端骨量,减少应力遮挡现象。根据我们在24个月时获得并在36个月时得到证实的数据,应力遮挡似乎在股骨矩水平最小程度发生。在大转子水平,我们看到良好的负荷分布维持了基线BMD;这些数据与文献数据相反,文献数据显示股骨矩水平BMD大幅增加(+12.9%),大转子水平BMD下降。通过对我们病例以及使用同一假体柄发表的病例的X线图像分析,大转子和股骨矩之间遇到的这些负荷转移差异似乎与股骨颈截骨水平及随之而来的假体位置(内翻/外翻)有关。

结论

我们得出结论,Metha<假体柄周围的假体周围骨吸收量似乎与手术技术和最终植入位置密切相关。

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