Zhang X-Y, Desborough M J, Shapiro S
Haematology Specialist Registrar, Department of Haematology, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford.
Clinical Research Fellow, NHS Blood and Transplant, John Radcliffe Hospital, Oxford, and Oxford Clinical Research in Transfusion Medicine, Nuffield Division of Clinical Laboratory Sciences, University of Oxford, Oxford.
Br J Hosp Med (Lond). 2017 Mar 2;78(3):165-169. doi: 10.12968/hmed.2017.78.3.165.
An understanding of how to counteract the anticoagulant effect of direct oral anticoagulants is essential in the event of haemorrhage, emergency surgery and overdose. This review summarizes strategies for the reversal of direct oral anticoagulants, including the use of novel agents.
了解如何对抗直接口服抗凝剂的抗凝作用,对于出血、急诊手术及药物过量情况至关重要。本综述总结了直接口服抗凝剂的逆转策略,包括新型药物的使用。