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逐户推动变革:开展教育外展活动以改善患有创伤后应激障碍的农村退伍军人的处方行为。

Cultivating change door to door: Educational outreach to improve prescribing practices in rural veterans with posttraumatic stress disorder.

作者信息

Montaño Macgregor, Bernardy Nancy C, Sherrieb Kathleen

机构信息

a Veterans Affairs Medical Center, White River Junction , Vermont , USA.

b National Center for PTSD , Veteran Affairs Medical Center, White River Junction , Vermont , USA.

出版信息

Subst Abus. 2017 Apr-Jun;38(2):129-134. doi: 10.1080/08897077.2017.1303423.

Abstract

BACKGROUND

Clinical guidelines for the management of posttraumatic stress disorder (PTSD) recommend against the use of benzodiazepines. Benzodiazepines and PTSD are both associated with addiction-related risks. The Department of Veterans Affairs (VA) prescribing trends show continued use of benzodiazepines and polysedative use in veterans with PTSD, particularly in rural areas. The authors examine the use of an educational intervention to improve pharmacologic management of veterans with PTSD in rural clinics.

METHODS

The VA Academic Detailing Service Informatics Toolset provides prescribing, demographic and risk factor data for veterans with PTSD treated at the White River Junction VA Medical Center (WRJ VA) and affiliated rural clinics in Vermont and New Hampshire. Individualized academic detailing visits were provided to clinicians identified by the informatics tool with the aim of increasing guideline-concordant care. Other educational efforts included traditional, didactic group education on evidence-based PTSD care and the development and dissemination of educational materials for clinicians and patients. Prescribing trends of benzodiazepines, off-label atypical antipsychotics, and prazosin were collected quarterly for 3 years (October 1, 2013, to September 30, 2016).

RESULTS

Prescribing rates of benzodiazepines during the educational intervention decreased from 13% to 9.3%. Use of off-label atypical antipsychotics, a class of medications not recommended for PTSD, stayed relatively flat at about 10%. Prescribing of prazosin, a medication recommended for treatment of trauma nightmares, increased from 9.8% to 14.3%.

CONCLUSIONS

Academic detailing and other educational programming appear to be effective for addressing gaps and lag in quality PTSD care and are associated with a positive trend of decreased benzodiazepine use. Efforts will continue, now with added focus on concurrent use of benzodiazepines and opioids and the use of off-label atypical antipsychotics in rural veterans with PTSD.

摘要

背景

创伤后应激障碍(PTSD)管理的临床指南不建议使用苯二氮䓬类药物。苯二氮䓬类药物和PTSD均与成瘾相关风险有关。美国退伍军人事务部(VA)的处方趋势显示,PTSD退伍军人中苯二氮䓬类药物的持续使用和多药联用情况,尤其是在农村地区。作者研究了使用教育干预措施来改善农村诊所中PTSD退伍军人的药物管理。

方法

VA学术循证医学服务信息工具集提供了在白河汇流处VA医疗中心(WRJ VA)以及佛蒙特州和新罕布什尔州的附属农村诊所接受治疗的PTSD退伍军人的处方、人口统计学和风险因素数据。通过信息工具确定的临床医生接受了个性化的学术循证医学访视,目的是增加符合指南的治疗。其他教育工作包括关于循证PTSD护理的传统理论性小组教育,以及为临床医生和患者开发和分发教育材料。在3年时间里(2013年10月1日至2016年9月30日),每季度收集苯二氮䓬类药物、非标签使用的非典型抗精神病药物和哌唑嗪的处方趋势。

结果

教育干预期间苯二氮䓬类药物的处方率从13%降至9.3%。不建议用于PTSD的一类药物——非标签使用的非典型抗精神病药物的使用相对平稳,约为10%。推荐用于治疗创伤后噩梦的药物哌唑嗪的处方率从9.8%增至14.3%。

结论

学术循证医学和其他教育项目似乎对解决PTSD优质护理中的差距和滞后有效,并且与苯二氮䓬类药物使用减少的积极趋势相关。相关工作将继续进行,现在将更多关注PTSD农村退伍军人中苯二氮䓬类药物和阿片类药物的同时使用以及非标签使用的非典型抗精神病药物的使用。

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