Liu Qiang, Li Bin, Zhao Jianping, Khan Shabana I, Liu Wen-Bin, Zeng Ting, Peng Cai-Yun, Cai Xiong, Peng Qinghua, Huang Huiyong, Khan Ikhlas A, Wang Wei
a TCM and Ethnomedicine Innovation & Development Laboratory , Sino-Luxemburg TCM Research Center, School of Pharmacy, Hunan University of Chinese Medicine , Changsha , China.
b National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi , Oxford , MS , USA.
Nat Prod Res. 2017 Aug;31(15):1725-1732. doi: 10.1080/14786419.2017.1289208. Epub 2017 Feb 28.
The present study investigated the chemical constituents of aerial part of Polygonum pubescens Blume. Twenty-two compounds 1-22 were obtained from petroleum ether and ethyl acetate extracts of aerial part of P. pubescens, including a new phenylpropanoide esters 1 and 21 known compounds. The structures were determined on the basis of spectroscopic and chemical methods. Sixteen compounds were assessed for their cytotoxic and anti-inflammatory activities. Several compounds showed effects on different targets.
