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Gene expression analysis of decitabine treated AML: high impact of tumor suppressor gene expression changes.

作者信息

Bohl Stephan R, Dolnik Anna, Jensen Thomas, Lang Katharina M, Hackanson Björn, Gaidzik Verena I, Paschka Peter, Knudsen Steen, Döhner Konstanze, Döhner Hartmut, Claus Rainer, Lübbert Michael, Bullinger Lars

机构信息

a Department of Internal Medicine III , University Hospital of Ulm , Ulm , Germany.

b Medical Prognosis Institute (MPI) , Hørsholm , Denmark.

出版信息

Leuk Lymphoma. 2017 Sep;58(9):1-4. doi: 10.1080/10428194.2017.1287360. Epub 2017 Feb 13.

DOI:10.1080/10428194.2017.1287360
PMID:28278722
Abstract
摘要

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引用本文的文献

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Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia.在一项1b/2期研究中,针对复发或难治性急性髓系白血病患者,将PLK1抑制剂onvansertib与地西他滨联合使用,结果发现剪接体突变与临床反应相关。
Ann Hematol. 2023 Nov;102(11):3049-3059. doi: 10.1007/s00277-023-05442-9. Epub 2023 Sep 13.
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Anti-Vascular Endothelial Growth Factor Effects of Sorafenib and Arsenic Trioxide in Acute Myeloid Leukemia Cell Lines.索拉非尼和三氧化二砷对急性髓系白血病细胞系的抗血管内皮生长因子作用
Asian Pac J Cancer Prev. 2017 Jun 25;18(6):1655-1661. doi: 10.22034/APJCP.2017.18.6.1655.