Long X
2nd Department of Oral and Maxillofacial Surgery, School of Stomatology, Wuhan University, Wuhan 430079, China.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2017 Mar 9;52(3):161-165. doi: 10.3760/cma.j.issn.1002-0098.2017.03.007.
Anterior disc displacement (ADD) of temporomandibular joint (TMJ) is regarded as one of the major findings in temporomandibular disorders (TMD). It is related to joint noise, pain, mandibular dysfunction, degenerative change and osteoarthritis. In the mean time, the pathological changes were found in synovial membrane and synovial fluid. Hyaluronic acid is a principal component of the synovial fluid which plays an important role in nutrition, lubrication, anti-inflammation and cartilage repair. The synthesis, molecule weight, and concentration of hyaluronic acid are decreased during TMD and cause TMJ degenerative changes. The clinical conditions, pathological changes, the mechanism of action for hyaluronic acid and the treatment of anterior disc displacement of TMJ are discussed in this article.
颞下颌关节（TMJ）前盘移位（ADD）被认为是颞下颌关节紊乱病（TMD）的主要表现之一。它与关节弹响、疼痛、下颌功能障碍、退行性改变和骨关节炎有关。同时，在滑膜和滑液中发现了病理变化。透明质酸是滑液的主要成分，在营养、润滑、抗炎和软骨修复中起重要作用。在TMD期间，透明质酸的合成、分子量和浓度降低，导致TMJ退行性改变。本文讨论了TMJ前盘移位的临床情况、病理变化、透明质酸的作用机制及治疗方法。
