Center for Microbial Pathogenesis, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA.
Cell Host Microbe. 2017 Mar 8;21(3):316-318. doi: 10.1016/j.chom.2017.02.017.
Recent studies demonstrate that the Ebola virus glycoprotein (GP) acquired an A82V change during the West Africa epidemic and that this change altered the capacity of GP to be activated by host factors, enhancing infection of human cells. How this may alter the outcome of disease remains to be determined.
最近的研究表明，埃博拉病毒糖蛋白（GP）在西非疫情期间获得了 A82V 突变，这一突变改变了 GP 被宿主因子激活的能力，增强了对人类细胞的感染。这将如何改变疾病的结果还有待确定。
