Department of Radiology and Cardiology, Centre for Heart Valve Innovation, University of British Columbia, Vancouver, British Columbia, Canada.
Leiden University Medical Center, Leiden, the Netherlands.
JACC Cardiovasc Imaging. 2017 Mar;10(3):286-295. doi: 10.1016/j.jcmg.2016.09.031.
The role of imaging in the diagnosis of valvular heart disease is well established through years of investigation and validation. However, the role of imaging in guiding the treatment decision-making for valvular heart disease is less well established, and there is a striking paucity of randomized trial data to help inform these decisions. Given this relative absence of randomized trial data, the present article highlights some of the most important knowledge gaps and defines meaningful opportunities for the field to help advance the care of patients with valvular heart disease in a cost-effective fashion. (The PARTNER 3-Trial: The Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis [P3]; NCT02675114; Medtronic Transcatheter Aortic Valve Replacement in Low Risk Patients; NCT02701283).
影像学在瓣膜性心脏病诊断中的作用经过多年的研究和验证已经得到充分确立。然而，影像学在指导瓣膜性心脏病治疗决策方面的作用尚未得到充分确立，并且缺乏有助于指导这些决策的随机临床试验数据。鉴于缺乏随机临床试验数据，本文重点介绍了一些最重要的知识空白，并为该领域确定了有意义的机会，以帮助以具有成本效益的方式推进瓣膜性心脏病患者的护理。（PARTNER 3 试验：SAPIEN 3 经导管主动脉瓣在低危主动脉瓣狭窄患者中的安全性和有效性[P3]；NCT02675114；美敦力低危患者经导管主动脉瓣置换术；NCT02701283）。
