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血液透析通路策略:血管外科医生的视角

Strategies for Hemodialysis Access: A Vascular Surgeon's Perspective.

作者信息

Scher Larry A, Shariff Saadat

机构信息

Department of Cardiothoracic and Vascular Surgery, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY.

Department of Cardiothoracic and Vascular Surgery, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY.

出版信息

Tech Vasc Interv Radiol. 2017 Mar;20(1):14-19. doi: 10.1053/j.tvir.2016.11.002. Epub 2016 Nov 29.

Abstract

Problems related to hemodialysis access are a significant cause of morbidity and mortality in patients with end-stage renal disease. Physicians of all specialties who are involved in the placement and maintenance of vascular access for hemodialysis must have a long-term strategy for sequential placement of autogenous fistulas, transpositions, and prosthetic grafts to preserve access sites and to avoid long-term use of tunneled dialysis catheters. The Fistula First and KDOQI initiatives have provided strategies and algorithms for access placement in patients with chronic kidney disease. Preservation of veins should begin before dialysis access is necessary to achieve the goal of creating a primary arteriovenous (AV) fistula or transposition suitable for cannulation when dialysis is initiated. Prosthetic and biologic grafts offer reasonable alternatives when autogenous access is not feasible. Newer graft materials and conduits are under evaluation to improve long-term outcomes. Use of tunneled dialysis catheters should be discouraged and they should be considered a last resort for long-term access. We present a strategy from the perspective of a vascular surgeon for the sequential placement of AV fistulas, venous transpositions, and AV grafts in these challenging patients. We also discuss specific concerns regarding hemodialysis access in difficult patient populations such as the elderly patient and the morbidly obese patient.

摘要

与血液透析通路相关的问题是终末期肾病患者发病和死亡的重要原因。所有参与血液透析血管通路置入和维护的专科医生都必须制定一项长期策略,按顺序进行自体动静脉内瘘、血管转位术和人工血管移植,以保留通路部位,并避免长期使用带隧道的透析导管。“内瘘优先”倡议和美国肾脏病基金会肾脏病预后质量倡议(KDOQI)为慢性肾脏病患者的通路置入提供了策略和算法。在有必要进行透析通路之前就应开始保护静脉,以实现创建一条在开始透析时适合穿刺的自体动静脉内瘘或血管转位术的目标。当自体通路不可行时,人工血管和生物移植物提供了合理的替代方案。新型移植物材料和管道正在评估中,以改善长期效果。应尽量避免使用带隧道的透析导管,应将其视为长期通路的最后手段。我们从血管外科医生的角度提出一项策略,用于在这些具有挑战性的患者中按顺序进行动静脉内瘘、静脉转位术和动静脉移植物的置入。我们还讨论了在老年患者和病态肥胖患者等困难患者群体中有关血液透析通路的具体问题。

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