Camara-Lemarroy Carlos R, Escobedo-Zúñiga Nicolás, Villarreal-Garza Estefania, García-Valadez Erick, Góngora-Rivera Fernando, Villarreal-Velázquez Héctor J
Neurology Service, University Hospital "Dr. José E. González", Universidad Autónoma de Nuevo León, Monterrey, N.L., Mexico.
Neurology Service, University Hospital "Dr. José E. González", Universidad Autónoma de Nuevo León, Monterrey, N.L., Mexico.
Pregnancy Hypertens. 2017 Jan;7:44-49. doi: 10.1016/j.preghy.2017.01.003. Epub 2017 Jan 16.
Posterior Reversible Encephalopathy Syndrome (PRES) and eclampsia share clinical characteristics and patients may present with a combination of these two entities. Our aim was to study the proportion of patients with eclampsia having evidence of PRES in their brain imaging.
Retrospective study of pregnant patients diagnosed as having eclampsia that underwent brain magnetic resonance imaging (MRI) during their hospitalization. MRI diagnosis of PRES was assessed by 2 investigators blinded to group.
We included a total of 29 patients with eclampsia, out of which 17 (58.6%) had MRI evidence of PRES. When patients with eclampsia and eclampsia/PRES were compared, there was no difference in demographic characteristics such as age, weight or multiparity. Patients with eclampsia/PRES had higher levels of creatinine, liver enzymes, mean platelet volume and there was a trend towards higher proteinuria. Infants of mothers with eclampsia/PRES also had worse 1min APGAR scores.
PRES appears to accompany eclampsia in over half of all cases. The clinical picture of patients with eclampsia with or without associated PRES is similar, but certain biochemical characteristics suggest that PRES might be indicative of a more severe disease process.
后部可逆性脑病综合征（PRES）与子痫具有共同的临床特征，患者可能同时出现这两种病症。我们的目的是研究子痫患者在脑部影像学检查中有PRES证据的比例。
对住院期间接受脑部磁共振成像（MRI）检查且被诊断为子痫的孕妇进行回顾性研究。由两名对分组情况不知情的研究人员评估MRI对PRES的诊断。
我们共纳入29例子痫患者，其中17例（58.6%）有MRI显示的PRES证据。比较子痫患者和子痫/PRES患者时，年龄、体重或多胎妊娠等人口统计学特征没有差异。子痫/PRES患者的肌酐、肝酶、平均血小板体积水平较高，蛋白尿也有升高趋势。子痫/PRES患者的婴儿1分钟阿氏评分也较低。
超过半数的子痫病例似乎伴有PRES。有或没有相关PRES的子痫患者临床表现相似，但某些生化特征表明PRES可能提示疾病进程更严重。
