来自五个亚洲国家的6E血清型临床分离株的基因组序列草图
Draft Genome Sequences of Clinical Isolates of Serotype 6E from Five Asian Countries.
作者信息
Park In Ho, Baek Jin Yang, Song Jae-Hoon, Ko Kwan Soo, Kim Kyung-Hyo
机构信息
Center for Vaccine Evaluation and Study, Medical Research Institute, Ewha Womans University, Seoul, Republic of Korea.
Asia Pacific Foundation for Infectious Diseases (APFID), Seoul, Republic of Korea.
出版信息
Genome Announc. 2017 Mar 9;5(10):e01728-16. doi: 10.1128/genomeA.01728-16.
Abstract
Although serotype 6E consistently expresses capsules of either vaccine-serotype 6A or 6B, certain genetic variants of serotype 6E may evade vaccine induced immunity. Thus, draft genome sequences from five clinical isolates of serotype 6E from each of five different Asian countries have been generated to provide insight into the genomic diversity in serotype 6E strains.
摘要
虽然血清型6E始终表达疫苗血清型6A或6B的荚膜，但血清型6E的某些基因变体可能逃避疫苗诱导的免疫。因此，已生成来自五个不同亚洲国家中每个国家的5株血清型6E临床分离株的基因组草图序列，以深入了解血清型6E菌株的基因组多样性。
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