Wu John Chung-Han, Lee Yi-Chieh, Cheng Yu-Chun, Wu Chih-Wei
Departments of Surgery; Otolaryngology; Ophthalmology; and Plastic Surgery, Chang Gung Memorial Hospital, College of Medicine, Chang Gung University.
Plast Reconstr Surg Glob Open. 2017 Feb 24;5(2):e1212. doi: 10.1097/GOX.0000000000001212. eCollection 2017 Feb.
Through-and-through oromandibular defects originate from surgical intervention of tumors of the oral cavity involving external skin, soft tissue, bone, and oral lining. Reconstruction of such composite defects is primarily achieved by 4 methods using distinct flaps in Chang Gung Memorial Hospital, including a single anterolateral thigh (ALT) flap, a single fibula flap, an osteomyocutaneous peroneal artery-based combined flap, and a combination of a fibular flap and an ALT flap, also known as a double flap.
In this retrospective study, 41 patients with through-and-through oromandibular defects reconstructed in Chang Gung Memorial Hospital Linkou branch from July 2007 to June 2009 using either of the 4 flaps were evaluated. Patients were divided into 4 groups according to the choice of flap, and their surgical outcomes, immediate and late complications, and their general condition were studied. Group 1 included 12 patients reconstructed with a single ALT flap, whereas group 2 included 15 patients using fibular flaps. Group 3 included 8 patients with osteomyocutaneous peroneal artery-based combined flaps, and group 4 included 6 patients who underwent reconstruction with double flaps.
Among all statistical results, we found that none of the differences regarding either patient demography or surgical outcomes between groups were statistically significant, except for squamous cell carcinoma staging.
Although the results were insignificant, trends within the data could be seen that support previous notions regarding each reconstruction method. For future studies, we strongly recommend a larger sample size.
贯通性口颌缺损源于口腔肿瘤的手术干预,涉及外部皮肤、软组织、骨骼和口腔黏膜。在长庚纪念医院,此类复合缺损的重建主要通过4种方法实现,即使用不同的皮瓣,包括单块股前外侧(ALT)皮瓣、单块腓骨皮瓣、以腓总动脉为蒂的骨肌皮联合皮瓣,以及腓骨皮瓣和ALT皮瓣的组合,即双皮瓣。
在这项回顾性研究中,对2007年7月至2009年6月在长庚纪念医院林口院区使用上述4种皮瓣之一重建贯通性口颌缺损的41例患者进行了评估。根据皮瓣的选择将患者分为4组,研究其手术结果、近期和远期并发症以及总体状况。第1组包括12例采用单块ALT皮瓣重建的患者,第2组包括15例使用腓骨皮瓣的患者。第3组包括8例采用以腓总动脉为蒂的骨肌皮联合皮瓣的患者,第4组包括6例接受双皮瓣重建的患者。
在所有统计结果中,我们发现除鳞状细胞癌分期外,各组之间在患者人口统计学或手术结果方面的差异均无统计学意义。
尽管结果无统计学意义,但数据中的趋势支持了先前关于每种重建方法的观点。对于未来的研究,我们强烈建议采用更大的样本量。