Yuen James C, Coleman Cathryn A, Erickson Stephen W
Division of Surgical Oncology, Banner MD Anderson, Gilbert, Ariz.; Department of Surgery, Baylor University Medical Center, Dallas, Tex.; and Genetic Epidemiology & Omics Research Program, RTI International, Research Triangle Park, N.C.
Plast Reconstr Surg Glob Open. 2017 Feb 13;5(2):e1231. doi: 10.1097/GOX.0000000000001231. eCollection 2017 Feb.
With a population in which 70% of the patients were overweight or obese, we reviewed retrospectively 135 breasts of 70 consecutive patients who underwent implant-based immediate breast reconstruction using freeze-dried AlloDerm as the acellular dermal matrix. Several obesity-related parameters were evaluated to determine their possible correlation to early postoperative complications. We found that breast width and surface area of AlloDerm usage correlated with the development of infection and mastectomy skin flap necrosis. Increased breast width and size of AlloDerm matrix implanted were correlated with higher rates of both minor and significant skin necrosis and of cellulitis. Body mass index was correlated with the development of cellulitis and minor and major skin necrosis but not with seroma or reconstruction failure. Preexisting breast cup size correlated with the development of seroma but not the other complications. We observed no statistically significant association between reconstruction failure and any of the parameters reviewed, but this is likely due to the small number of failures in our data set ( = 10).
在70%的患者超重或肥胖的人群中，我们回顾性研究了连续70例接受以冻干异体真皮（AlloDerm）为脱细胞真皮基质的即刻乳房植入重建手术患者的135个乳房。评估了几个与肥胖相关的参数，以确定它们与术后早期并发症的可能相关性。我们发现乳房宽度和AlloDerm使用面积与感染及乳房切除皮瓣坏死的发生相关。乳房宽度增加和植入的AlloDerm基质面积增大与轻微和严重皮肤坏死及蜂窝织炎的发生率较高相关。体重指数与蜂窝织炎及轻微和严重皮肤坏死的发生相关，但与血清肿或重建失败无关。术前乳房罩杯尺寸与血清肿的发生相关，但与其他并发症无关。我们观察到重建失败与所审查的任何参数之间均无统计学显著关联，但这可能是由于我们数据集中的失败病例数较少（=10）。
