Fernandes Paula Frassinetti Castelo Branco Camurça, Siqueira Reed André, Girão Evelyne Santana, Siqueira Rainne André, Mota Márcia Uchoa, Marques Leyla Castelo Branco Fernandes, Andrade Silvana Cristina Albuquerque, Barroso Wilson Mendes, Silva Sônia Leite, Rodrigues Dos Santos Bruno Gomes, de Oliveira Claúdia Maria Costa
Paula Frassinetti Castelo Branco Camurça Fernandes, Evelyne Santana Girão, Márcia Uchoa Mota, Leyla Castelo Branco Fernandes Marques, Silvana Cristina Albuquerque Andrade, Wilson Mendes Barroso, Sônia Leite Silva, Bruno Gomes Rodrigues dos Santos, Claúdia Maria Costa de Oliveira, Kidney Transplant Unit, Hospital Universitário Walter Cantídio, Universidade Federal do Ceará, Fortaleza, CE 60430-370, Brazil.
World J Transplant. 2017 Feb 24;7(1):57-63. doi: 10.5500/wjt.v7.i1.57.
To present clinical characteristics from renal transplant recipients with dengue fever and its impact on graft function.
We retrospectively evaluated 11 renal transplant recipients (RTR) with dengue infection confirmed by laboratory test, between January 2007 and July 2012, transplanted in the Renal Transplant Center of Walter Cantídio University Hospital from Federal University of Ceará.
Positive dengue serology (IgM) was found in all patients. The mean time between transplant and dengue infection was 43 mo. Fever was presented in all patients. Nine patients presented with classical dengue and two (18%) with dengue hemorrhagic fever. All cases had satisfactory evolution with complete recovery of the symptoms. The time for symptom resolution varied from 2 to 20 d, with an average of 9 d. An increase of creatinine after the infection was observed in three (27.2%) patients with no clinically impact on the kidney graft function.
RTR with dengue infection seems to have a clinical presentation and evolution similar to those seen in the general population, with no long-term damage to patient and to the graft.
呈现肾移植受者登革热的临床特征及其对移植肾功能的影响。
我们回顾性评估了2007年1月至2012年7月间在塞阿拉联邦大学沃尔特·坎蒂迪奥大学医院肾移植中心接受移植的11例经实验室检查确诊为登革热感染的肾移植受者（RTR）。
所有患者登革热血清学检查（IgM）均呈阳性。移植与登革热感染之间的平均时间为43个月。所有患者均出现发热。9例患者表现为典型登革热，2例（18%）表现为登革出血热。所有病例病情进展顺利，症状完全恢复。症状缓解时间为2至20天，平均为9天。3例（27.2%）患者感染后肌酐升高，但对肾移植功能无临床影响。
感染登革热的肾移植受者的临床表现和病情进展似乎与普通人群相似，对患者和移植肾均无长期损害。
