Abdel-Azim N E, Ismail S A, Fathy E
Department of Dermatology, Venereology and Andrology, Faculty of Medicine, Assiut University, Assiut, Egypt.
Arch Dermatol Res. 2017 May;309(4):311-314. doi: 10.1007/s00403-017-1727-2. Epub 2017 Mar 9.
Pityriasis rubra pilaris (PRP) and plaque psoriasis (PP) are two distinctive erythemato-squamous skin diseases that often have to be differentiated from each other and from other similar dermatoses. Dermoscopy has been proven to aid the clinical diagnosis of several inflammatory disorders, minimizing the need for skin biopsy. Our aim was to determine the dermoscopic patterns of PRP compared to PP and to assess the significance of certain dermoscopic criteria in the diagnosis of PRP. This case-control study included 11 patients with biopsy proven PRP and 25 patients with biopsy proven plaque psoriasis. The most recently developed lesion of each patient was examined by non-contact dermoscopy. Whitish keratotic plugs and linear vessels in yellowish background are significant dermoscopic features of PRP compared to white diffuse scales and dotted vessels in a light red background in PP. In conclusion, PRP and PP reveal specific distinguishing dermoscopic patterns that may assist in their clinical diagnosis and may also be useful for the differential diagnosis from other resembling dermatoses.
红皮病型毛发红糠疹(PRP)和斑块状银屑病(PP)是两种不同的红斑鳞屑性皮肤病,常常需要相互鉴别,并与其他类似的皮肤病相区分。皮肤镜检查已被证明有助于多种炎症性疾病的临床诊断,从而减少皮肤活检的必要性。我们的目的是确定PRP与PP相比的皮肤镜特征模式,并评估某些皮肤镜标准在PRP诊断中的意义。这项病例对照研究纳入了11例经活检证实为PRP的患者和25例经活检证实为斑块状银屑病的患者。通过非接触式皮肤镜检查每位患者最新出现的皮损。与PP中淡红色背景下的白色弥漫性鳞屑和点状血管相比,PRP的皮肤镜显著特征为白色角化栓和淡黄色背景下的线状血管。总之,PRP和PP呈现出特定的、可资鉴别的皮肤镜特征模式,这可能有助于它们的临床诊断,也可能有助于与其他类似皮肤病进行鉴别诊断。