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驱动癌症进化。

Driving cancer evolution.

机构信息

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.

Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, United States.

出版信息

Elife. 2017 Mar 10;6:e25431. doi: 10.7554/eLife.25431.

Abstract

Tumor-growth-factor-beta signaling helps cancer cells to evolve and become resistant to drugs by down-regulating accurate DNA repair.

摘要

肿瘤生长因子-β信号通过下调精确的 DNA 修复帮助癌细胞进化并对药物产生耐药性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a557/5345930/45e609e2601f/elife-25431-fig1.jpg

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