Dabiri Sasan, Yazdani Nasrin, Esfahani Mahdis, Tari Niloufar, Adil Susan, Mahvi Zahra, Rezazadeh Nima
Otorhinolaryngology Research Center, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Acta Med Iran. 2017 Feb;55(2):123-127.
Meniere's disease is the disorder of inner ear characterized by vertigo, tinnitus and sensorineural hearing loss. The vestibular evoked myogenic potential (VEMP) test could be useful in the analysis of saccular function, and diagnosis of Meniere's disease. In this study, we've analyzed the saccular function, using VEMP test in different groups of Meniere's disease. Patients were categorized as possible, probable or definite Meniere's disease groups according to the guideline of American Academy of Otolaryngology-Head and Neck Surgery. The exclusion criteria were neuromuscular system diseases, diseases of central nervous system, inner ear disorders, conductive hearing loss, a history of ototoxic drug consumption, being a drug abuser and a positive history of inner ear surgery or manipulations. The VEMP test is the recording of positive and negative waves from sternocleidomastoid muscle that is made by an auditory click to the ear. From the total of 100 patients, the waves of VEMP test was seen in 59 patients which 19 patients had abnormal amplitude, and latency and 40 patients were with normally recorded waves. There was a significant relationship between the severity of hearing loss and a VEMP test without any recorded waves. Most of the cases with 'no wave recorded' VEMP test, were patients with severe hearing loss. However, there wasn't any relation between the pattern of hearing loss and 'no wave recorded' VEMP test. VEMP test could be a valuable diagnostic clue especially in patients with definite Meniere's disease.
梅尼埃病是一种以内耳紊乱为特征的疾病，表现为眩晕、耳鸣和感音神经性听力损失。前庭诱发肌源性电位（VEMP）测试有助于分析球囊功能及梅尼埃病的诊断。在本研究中，我们使用VEMP测试分析了不同组梅尼埃病患者的球囊功能。根据美国耳鼻咽喉-头颈外科学会的指南，患者被分为可能、很可能或确诊的梅尼埃病组。排除标准包括神经肌肉系统疾病、中枢神经系统疾病、内耳疾病、传导性听力损失、耳毒性药物使用史、药物滥用史以及内耳手术或操作史。VEMP测试是通过向耳朵发出听觉咔嗒声来记录胸锁乳突肌的正负波。在总共100名患者中，59名患者出现了VEMP测试波形，其中19名患者的波幅、潜伏期异常，40名患者的波形记录正常。听力损失的严重程度与未记录到任何波形的VEMP测试之间存在显著关系。大多数VEMP测试“未记录到波形”的病例是重度听力损失患者。然而，听力损失模式与“未记录到波形”的VEMP测试之间没有任何关系。VEMP测试可能是一个有价值的诊断线索，尤其是对于确诊的梅尼埃病患者。
