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一种感染产毒素定鞭藻微小原甲藻的双链DNA巨型病毒的分离与鉴定

Isolation and Characterization of a Double Stranded DNA Megavirus Infecting the Toxin-Producing Haptophyte Prymnesium parvum.

作者信息

Wagstaff Ben A, Vladu Iulia C, Barclay J Elaine, Schroeder Declan C, Malin Gill, Field Robert A

机构信息

Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.

Marine Biological Association of the UK, Plymouth PL1 2PB, UK.

出版信息

Viruses. 2017 Mar 9;9(3):40. doi: 10.3390/v9030040.

DOI:10.3390/v9030040
PMID:28282930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5371795/
Abstract

is a toxin-producing haptophyte that causes harmful algal blooms globally, leading to large-scale fish kills that have severe ecological and economic implications. For the model haptophyte, , it has been shown that large dsDNA viruses play an important role in regulating blooms and therefore biogeochemical cycling, but much less work has been done looking at viruses that infect , or the role that these viruses may play in regulating harmful algal blooms. In this study, we report the isolation and characterization of a lytic nucleo-cytoplasmic large DNA virus (NCLDV) collected from the site of a harmful bloom. In subsequent experiments, this virus was shown to infect cultures of sp. and showed phylogenetic similarity to the extended family of algal viruses.

摘要

是一种产生毒素的定鞭藻,在全球范围内引发有害藻华,导致大规模鱼类死亡,具有严重的生态和经济影响。对于模式定鞭藻……,已表明大型双链DNA病毒在调节藻华进而生物地球化学循环中发挥重要作用,但针对感染……的病毒或这些病毒在调节有害藻华中可能发挥的作用的研究要少得多。在本研究中,我们报告了从有害藻华发生地分离并鉴定的一种裂解性核质大型DNA病毒(NCLDV)。在后续实验中,该病毒被证明可感染……种的培养物,并与藻类病毒的扩展……家族表现出系统发育相似性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2856/5371795/528bdfffa0f2/viruses-09-00040-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2856/5371795/e806f9a1c521/viruses-09-00040-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2856/5371795/01a62968871d/viruses-09-00040-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2856/5371795/e73c54b181f6/viruses-09-00040-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2856/5371795/528bdfffa0f2/viruses-09-00040-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2856/5371795/e806f9a1c521/viruses-09-00040-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2856/5371795/01a62968871d/viruses-09-00040-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2856/5371795/e73c54b181f6/viruses-09-00040-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2856/5371795/528bdfffa0f2/viruses-09-00040-g004.jpg

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