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加纳中风幸存者睡眠呼吸暂停风险的患病率及预测因素

Prevalence and Predictors of Sleep Apnea Risk among Ghanaian Stroke Survivors.

作者信息

Sarfo Fred Stephen, Jenkins Carolyn, Mensah Nathaniel Adusei, Saulson Raelle, Sarfo-Kantanka Osei, Singh Arti, Nichols Michelle, Qanungo Suparna, Ovbiagele Bruce

机构信息

Kwame Nkrumah University of Science & Technology, Kumasi, Ghana; Komfo Anokye Teaching Hospital, Kumasi, Ghana.

Medical University of South Carolina, Charleston, South Carolina.

出版信息

J Stroke Cerebrovasc Dis. 2017 Jul;26(7):1602-1608. doi: 10.1016/j.jstrokecerebrovasdis.2017.02.027. Epub 2017 Mar 7.

Abstract

BACKGROUND AND PURPOSE

Sleep apnea (SA) has emerged as a potent risk factor for stroke recurrence and mortality. The burden of SA among stroke survivors in sub-Saharan Africa where stroke incidence and mortality are escalating is unknown. We sought to assess the prevalence of SA risk and its clinical correlates and predictors among Ghanaian stroke survivors.

METHODS

This cross-sectional study involved 200 consecutive stroke survivors attending a neurology clinic in a tertiary medical center in Kumasi, Ghana. The validated Berlin, STOP-BANG, and Epworth Sleepiness Scale questionnaires were administered to all eligible subjects to assess SA risk and daytime somnolence, and their demographic and clinical information, health-related quality of life, and symptoms of depression were collected using the questionnaires.

RESULTS

The median (interquartile range) age of stroke survivors was 62 (52-72) years and 52.5% were male. Ninety-nine (49.5%) subjects were identified as high risk for SA using the Berlin questionnaire, whereas 26 (13%), 137 (68.5%), and 37 (18.5%) subjects were classified as low, intermediate, and high risk for SA, respectively, using the STOP-BANG questionnaire. Patients at high risk of SA were significantly older, used excess alcohol, and were less able to perform activities of daily living, although their mean National Institutes of Health Stroke Scale scores were significantly lower than those with low risk for SA. None of the stroke survivors had ever been screened for SA.

CONCLUSIONS

One out of every 2 stroke survivors attending a neurology clinic in Ghana is at high risk for undiagnosed SA. Greater regional awareness about SA presence and outcomes among patients and providers is warranted.

摘要

背景与目的

睡眠呼吸暂停(SA)已成为中风复发和死亡的一个重要危险因素。在撒哈拉以南非洲地区,中风发病率和死亡率不断上升,中风幸存者中SA的负担尚不清楚。我们试图评估加纳中风幸存者中SA风险的患病率及其临床相关性和预测因素。

方法

这项横断面研究纳入了连续200例在加纳库马西一家三级医疗中心的神经科诊所就诊的中风幸存者。对所有符合条件的受试者进行经过验证的柏林问卷、STOP-BANG问卷和爱泼华嗜睡量表问卷调查,以评估SA风险和日间嗜睡情况,并使用问卷收集他们的人口统计学和临床信息、健康相关生活质量以及抑郁症状。

结果

中风幸存者的年龄中位数(四分位间距)为62(52 - 72)岁,男性占52.5%。使用柏林问卷,99名(49.5%)受试者被确定为SA高风险,而使用STOP-BANG问卷时,分别有26名(13%)、137名(68.5%)和37名(18.5%)受试者被分类为SA低风险、中风险和高风险。SA高风险患者年龄显著更大,饮酒过量,日常生活活动能力较差,尽管他们的平均美国国立卫生研究院卒中量表评分显著低于SA低风险患者。没有中风幸存者曾接受过SA筛查。

结论

在加纳一家神经科诊所就诊的每2名中风幸存者中就有1名存在未被诊断的SA高风险。患者和医疗服务提供者对SA的存在及其后果需要有更高的区域认识。

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本文引用的文献

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