Maier P, Lapp T, Reinhard T
Klinik für Augenheilkunde, Albert-Ludwigs-Universität Freiburg, Killianstr. 5, 79106, Freiburg, Deutschland.
Ophthalmologe. 2017 Jun;114(6):514-524. doi: 10.1007/s00347-017-0473-3.
Patients with atopic dermatitis frequently complain of ocular symptoms. The general dermatitis can directly affect the periocular skin and patients often present with chronic atopic blepharokeratoconjunctivitis. Early diagnosis of the characteristic ophthalmological alterations, such as blepharitis, allergic conjunctivitis, keratoconjunctivitis sicca, conjunctival scarring with formation of symblepharon and lid malpositioning, filiform keratitis, corneal plaques, (persistent) epithelial defects, corneal ulcers and keratoconus as well as appropriate stage-adapted treatment, including lid hygiene with preservative-free lubricants, topical and sometimes systemic anti-inflammatory therapy and surgical treatment are important for patients to prevent long-term damage of the ocular surface leading to severe visual impairment.
特应性皮炎患者经常抱怨眼部症状。全身性皮炎可直接影响眼周皮肤，患者常表现为慢性特应性睑缘角结膜炎。早期诊断特征性眼科改变，如睑缘炎、过敏性结膜炎、干燥性角结膜炎、结膜瘢痕形成睑球粘连和眼睑位置异常、丝状角膜炎、角膜斑块、（持续性）上皮缺损、角膜溃疡和圆锥角膜，以及进行适当的分期适应性治疗，包括使用无防腐剂润滑剂进行眼睑清洁、局部及有时全身性抗炎治疗和手术治疗，对于患者预防眼表长期损害导致严重视力障碍很重要。
