Garcia M, Maudelonde T
INSERM U 148, Unité d'Endocrinologie Cellulaire et Moléculaire, Montpellier.
J Chir (Paris). 1987 Nov;124(11):615-21.
Basic studies developed from human cell lines or tissue biopsies have allowed to isolate monoclonal antibodies and complementary DNAs specific for tumoral antigens and rare proteins implicated in the control of cancer growth and invasiveness. Present clinical studies indicate that some molecular probes display a potential value as markers of tissue specificity, of hormone dependency or prognosis in breast and endometrial cancers.
源自人类细胞系或组织活检的基础研究已能够分离出针对肿瘤抗原以及与癌症生长和侵袭控制相关的稀有蛋白质的单克隆抗体和互补DNA。目前的临床研究表明，一些分子探针在乳腺癌和子宫内膜癌中作为组织特异性、激素依赖性或预后的标志物显示出潜在价值。
