脂质体共包封两种新型铕配合物和阿霉素的研究：荧光研究。
Liposomal Co-Encapsulation of Two Novel Europium Complexes and Doxorubicin: Fluorescence Study.
机构信息
Department of Nuclear and Medical Physics, V.N. Karazin Kharkov National University, 4 Svobody Sq, Kharkov, 61072, Ukraine.
, 19-32 Geroyev Truda Str, Kharkov, 61072, Ukraine.
出版信息
J Fluoresc. 2017 Jul;27(4):1359-1363. doi: 10.1007/s10895-017-2070-x. Epub 2017 Mar 10.
PMID:28283899
Abstract
The present study was undertaken to design the novel liposomal drug formulation containing doxorubicin and europium coordination complexes. It was shown that co-encapsulation of the drugs facilitates the partitioning and permeation of lanthanides into the lipid bilayer. The obtained results suggest that new drug platform may have potential application in the design of novel antitumor agents.
摘要
本研究旨在设计包含阿霉素和铕配合物的新型脂质体药物制剂。研究表明，药物的共包封有利于镧系元素进入脂质双层的分配和渗透。研究结果表明，新的药物平台可能在新型抗肿瘤药物的设计中有潜在的应用。
Zotero 插件